ELI LILLY vs Merck (LLY vs MRK)
Side by side from their SEC filings: revenue, margins, growth, returns and valuation, plus short interest, insider activity and institutional ownership.
ELI LILLY has grown revenue faster over the last 4 fiscal years (+130.2% cumulative vs +33.5%). Merck trades at the lower trailing P/E (34.9x vs 42.0x).
About ELI LILLY
Eli Lilly and Company discovers, develops, manufactures, and markets human pharmaceutical products worldwide. Its main products include treatments for diabetes, oncology, immunology, and neuroscience conditions. The company serves healthcare providers, wholesalers, pharmacies, hospitals, and patients in approximately 90 countries.
About Merck
Merck & Co., Inc. is a pharmaceutical company that develops and sells prescription medicines, vaccines, and animal health products. It serves healthcare providers, patients, and animal health customers worldwide. The company also collaborates with other firms to develop and commercialize various pharmaceutical products.
Head to head (LLY FY2025 vs MRK FY2025)
| Metric | LLYFY2025 | MRKFY2025 |
|---|---|---|
| Revenue | $65.18B | $65.01B |
| Revenue growth (YoY) | 44.7% | 1.3% |
| Gross margin | 83.0% | 74.8% |
| Operating margin | — | — |
| Net margin | 31.7% | 28.1% |
| Net income | $20.64B | $18.25B |
| Diluted EPS | $22.95 | $7.28 |
| FCF margin | — | 19.0% |
| ROE | 77.8% | 34.7% |
| Debt / equity | 1.5× | 0.9× |
| Market cap | $1.05T | $306.33B |
| P/E (TTM) | 42.0× | 34.9× |
Fundamentals are from each company’s SEC filings (LLY FY2025, MRK FY2025). P/E and market cap are derived from recent market prices and update daily.
Five-year trend (as reported)
| Revenue | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 |
|---|---|---|---|---|---|
| LLY | $28.32B | $28.54B | $34.12B | $45.04B | $65.18B |
| MRK | $48.70B | $59.28B | $60.12B | $64.17B | $65.01B |
Peer standing
Where each company ranks among the 198 pharmaceutical companies, on the same scale. Each figure is ranked only against peers that report it. Percentiles describe position in the distribution, not a rating.
| Metric | LLY | MRK |
|---|---|---|
| Gross margin | 83.0%82nd percentile of 68 | 74.8%67th percentile of 68 |
| Net margin | 31.7%86th percentile of 121 | 28.1%82nd percentile of 121 |
| Revenue growth (YoY) | +44.7%72nd percentile of 186 | +1.3%36th percentile of 186 |
| ROE | 77.8%99th percentile of 167 | 34.7%91st percentile of 167 |
| P/E (TTM) | 42.0×80th percentile of 61 | 34.9×77th percentile of 61 |
| Debt / equity | 1.54×88th percentile of 65 | 0.89×77th percentile of 65 |
| Short interest (days to cover) | 2.58d24th percentile of 197 | 2.30d21st percentile of 197 |
Short interest
| FINRA settlement data | LLY | MRK |
|---|---|---|
| Shares sold short | 9.4M | 31.4M |
| Change vs prior settlement | -3.2% | +3.7% |
| Days to cover | 2.58 | 2.30 |
| As of settlement | 2026-06-30 | 2026-06-30 |
Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data; republishing or redistributing it is not permitted. Not presented as a percentage of float. No FINRA endorsement of this product is implied.
Insider activity (last 90 days)
| Form 4 open-market activity | LLY | MRK |
|---|---|---|
| Buys | 0 | — |
| Sells | 3 ($18.6M) | — |
Open-market purchases and sales reported on SEC Form 4 (grants, exercises and tax withholding excluded). For context, about 16% of covered companies saw any open-market insider buy in a 90-day window.
Held by the same investors
9 tracked 13F managers hold both ELI LILLY and Merck as of their latest quarterly filings: AQR Capital Management, Citadel Advisors, D. E. Shaw, Dodge & Cox, Gotham Asset Management, Harris Associates (Oakmark), Millennium Management, Point72 Asset Management, Two Sigma Investments. See which superinvestors hold your own portfolio with the smart money checker.
Go deeper
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Data sourced from SEC EDGAR (public domain). Figures are as-reported and may be unaudited or restated; verify against the source filings before relying on them. Comparisons are descriptive (higher or lower on a reported figure), not a rating or a recommendation. Informational only. Not investment advice.