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Bristol Myers Squibb vs ELI LILLY (BMY vs LLY)

Side by side from their SEC filings: revenue, margins, growth, returns and valuation, plus short interest, insider activity and institutional ownership.

ELI LILLY is the larger company by revenue ($65.2B vs $48.2B) and market value ($1.1T vs $117.6B). ELI LILLY has grown revenue faster over the last 4 fiscal years (+130.2% cumulative vs +3.9%). Bristol Myers Squibb trades at the lower trailing P/E (16.1x vs 42.0x).

About Bristol Myers Squibb

Bristol Myers Squibb is a biopharmaceutical company that discovers, develops, manufactures, markets, and sells innovative medicines for serious diseases. Its main products include biologics, small molecule drugs, CAR-T cell therapies, and radiopharmaceuticals used to treat conditions such as cancer, autoimmune diseases, cardiovascular and neurological disorders. The company serves patients worldwide through wholesalers, distributors, specialty pharmacies, hospitals, clinics, and government agencies.

About ELI LILLY

Eli Lilly and Company discovers, develops, manufactures, and markets human pharmaceutical products worldwide. Its main products include treatments for diabetes, oncology, immunology, and neuroscience conditions. The company serves healthcare providers, wholesalers, pharmacies, hospitals, and patients in approximately 90 countries.

Head to head (BMY FY2025 vs LLY FY2025)

MetricBMYFY2025LLYFY2025
Revenue$48.19B$65.18B
Revenue growth (YoY)-0.2%44.7%
Gross margin71.1%83.0%
Operating margin
Net margin14.6%31.7%
Net income$7.05B$20.64B
Diluted EPS$3.46$22.95
FCF margin26.7%
ROE38.1%77.8%
Debt / equity2.3×1.5×
Market cap$117.58B$1.05T
P/E (TTM)16.1×42.0×

Fundamentals are from each company’s SEC filings (BMY FY2025, LLY FY2025). P/E and market cap are derived from recent market prices and update daily.

Five-year trend (as reported)

RevenueFY2021FY2022FY2023FY2024FY2025
BMY$46.38B$46.16B$45.01B$48.30B$48.19B
LLY$28.32B$28.54B$34.12B$45.04B$65.18B
Net incomeFY2021FY2022FY2023FY2024FY2025
BMY$6.99B$6.33B$8.03B$-8.95B$7.05B
LLY$5.58B$6.24B$5.24B$10.59B$20.64B
Operating marginFY2021FY2022FY2023FY2024FY2025
BMY
LLY

Peer standing

Where each company ranks among the 198 pharmaceutical companies, on the same scale. Each figure is ranked only against peers that report it. Percentiles describe position in the distribution, not a rating.

MetricBMYLLY
Gross margin
71.1%57th percentile of 68
83.0%82nd percentile of 68
Net margin
14.6%76th percentile of 121
31.7%86th percentile of 121
Revenue growth (YoY)
-0.2%34th percentile of 186
+44.7%72nd percentile of 186
ROE
38.1%93rd percentile of 167
77.8%99th percentile of 167
P/E (TTM)
16.1×48th percentile of 61
42.0×80th percentile of 61
Debt / equity
2.32×91st percentile of 65
1.54×88th percentile of 65
Short interest (days to cover)
2.47d22nd percentile of 197
2.58d24th percentile of 197

Short interest

FINRA settlement dataBMYLLY
Shares sold short40.5M9.4M
Change vs prior settlement+2.4%-3.2%
Days to cover2.472.58
As of settlement2026-06-302026-06-30

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data; republishing or redistributing it is not permitted. Not presented as a percentage of float. No FINRA endorsement of this product is implied.

Insider activity (last 90 days)

Form 4 open-market activityBMYLLY
Buys0
Sells3 ($18.6M)

Open-market purchases and sales reported on SEC Form 4 (grants, exercises and tax withholding excluded). For context, about 16% of covered companies saw any open-market insider buy in a 90-day window.

Held by the same investors

10 tracked 13F managers hold both Bristol Myers Squibb and ELI LILLY as of their latest quarterly filings: AQR Capital Management, Bridgewater Associates, Citadel Advisors, D. E. Shaw, Dodge & Cox, Gotham Asset Management, Millennium Management, Point72 Asset Management, Renaissance Technologies, Two Sigma Investments. See which superinvestors hold your own portfolio with the smart money checker.

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Data sourced from SEC EDGAR (public domain). Figures are as-reported and may be unaudited or restated; verify against the source filings before relying on them. Comparisons are descriptive (higher or lower on a reported figure), not a rating or a recommendation. Informational only. Not investment advice.