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Johnson & Johnson vs ELI LILLY (JNJ vs LLY)

Side by side from their SEC filings: revenue, margins, growth, returns and valuation, plus short interest, insider activity and institutional ownership.

Johnson & Johnson is the larger company by revenue ($94.2B vs $65.2B). ELI LILLY carries the larger market value ($1.1T vs $609.1B). ELI LILLY has grown revenue faster over the last 4 fiscal years (+130.2% cumulative vs +19.6%). Johnson & Johnson trades at the lower trailing P/E (29.0x vs 42.0x).

About Johnson & Johnson

Johnson & Johnson is a global healthcare company that operates through two main segments: Innovative Medicine and MedTech. The Innovative Medicine segment develops and sells prescription medicines for various therapeutic areas including oncology, immunology, neuroscience, infectious diseases, and cardiovascular conditions. The MedTech segment designs and manufactures medical devices and products used in cardiovascular care, orthopaedics, surgery, and vision, serving healthcare professionals, hospitals, and eye care providers worldwide.

About ELI LILLY

Eli Lilly and Company discovers, develops, manufactures, and markets human pharmaceutical products worldwide. Its main products include treatments for diabetes, oncology, immunology, and neuroscience conditions. The company serves healthcare providers, wholesalers, pharmacies, hospitals, and patients in approximately 90 countries.

Head to head (JNJ FY2025 vs LLY FY2025)

MetricJNJFY2025LLYFY2025
Revenue$94.19B$65.18B
Revenue growth (YoY)6.0%44.7%
Gross margin67.9%83.0%
Operating margin
Net margin28.5%31.7%
Net income$26.80B$20.64B
Diluted EPS$11.03$22.95
FCF margin20.9%
ROE32.9%77.8%
Debt / equity0.5×1.5×
Market cap$609.12B$1.05T
P/E (TTM)29.0×42.0×

Fundamentals are from each company’s SEC filings (JNJ FY2025, LLY FY2025). P/E and market cap are derived from recent market prices and update daily.

Five-year trend (as reported)

RevenueFY2021FY2022FY2023FY2024FY2025
JNJ$78.74B$79.99B$85.16B$88.82B$94.19B
LLY$28.32B$28.54B$34.12B$45.04B$65.18B
Net incomeFY2021FY2022FY2023FY2024FY2025
JNJ$20.88B$17.94B$35.15B$14.07B$26.80B
LLY$5.58B$6.24B$5.24B$10.59B$20.64B
Operating marginFY2021FY2022FY2023FY2024FY2025
JNJ
LLY

Peer standing

Where each company ranks among the 198 pharmaceutical companies, on the same scale. Each figure is ranked only against peers that report it. Percentiles describe position in the distribution, not a rating.

MetricJNJLLY
Gross margin
67.9%51st percentile of 68
83.0%82nd percentile of 68
Net margin
28.5%83rd percentile of 121
31.7%86th percentile of 121
Revenue growth (YoY)
+6.0%43rd percentile of 186
+44.7%72nd percentile of 186
ROE
32.9%90th percentile of 167
77.8%99th percentile of 167
P/E (TTM)
29.0×73rd percentile of 61
42.0×80th percentile of 61
Debt / equity
0.48×47th percentile of 65
1.54×88th percentile of 65
Short interest (days to cover)
2.48d22nd percentile of 197
2.58d24th percentile of 197

Short interest

FINRA settlement dataJNJLLY
Shares sold short26.6M9.4M
Change vs prior settlement-0.4%-3.2%
Days to cover2.482.58
As of settlement2026-06-302026-06-30

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data; republishing or redistributing it is not permitted. Not presented as a percentage of float. No FINRA endorsement of this product is implied.

Insider activity (last 90 days)

Form 4 open-market activityJNJLLY
Buys00
Sells1 ($2.4M)3 ($18.6M)

Open-market purchases and sales reported on SEC Form 4 (grants, exercises and tax withholding excluded). For context, about 16% of covered companies saw any open-market insider buy in a 90-day window.

Held by the same investors

9 tracked 13F managers hold both Johnson & Johnson and ELI LILLY as of their latest quarterly filings: AQR Capital Management, Bridgewater Associates, Citadel Advisors, D. E. Shaw, Dodge & Cox, Gotham Asset Management, Millennium Management, Soros Fund Management, Two Sigma Investments. See which superinvestors hold your own portfolio with the smart money checker.

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Data sourced from SEC EDGAR (public domain). Figures are as-reported and may be unaudited or restated; verify against the source filings before relying on them. Comparisons are descriptive (higher or lower on a reported figure), not a rating or a recommendation. Informational only. Not investment advice.