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Johnson & Johnson vs ELI LILLY (JNJ vs LLY)

Side by side from their SEC filings: revenue, margins, growth, returns and valuation, plus short interest, insider activity and institutional ownership.

Johnson & Johnson is the larger company by revenue ($94.2B vs $65.2B). ELI LILLY carries the larger market value ($1.0T vs $653.5B). ELI LILLY has grown revenue faster over the last 4 fiscal years (+130.2% cumulative vs +19.6%). Johnson & Johnson trades at the lower trailing P/E (30.9x vs 38.9x).

About Johnson & Johnson

Johnson & Johnson is a global healthcare company that operates through two main segments: Innovative Medicine and MedTech. The Innovative Medicine segment develops and sells prescription medicines for various therapeutic areas including oncology, immunology, neuroscience, infectious diseases, and cardiovascular conditions. The MedTech segment designs and manufactures medical devices and products used in cardiovascular care, orthopaedics, surgery, and vision, serving healthcare professionals, hospitals, and eye care providers worldwide.

About ELI LILLY

Eli Lilly and Company discovers, develops, manufactures, and markets human pharmaceutical products worldwide. Its main products include treatments for diabetes, oncology, immunology, and neuroscience conditions. The company serves healthcare providers, wholesalers, pharmacies, hospitals, and patients in approximately 90 countries.

Head to head (JNJ FY2025 vs LLY FY2025)

MetricJNJFY2025LLYFY2025
Revenue$94.19B$65.18B
Revenue growth (YoY)6.0%44.7%
Gross margin67.9%83.0%
Operating margin
Net margin28.5%31.7%
Net income$26.80B$20.64B
Diluted EPS$11.03$22.95
FCF margin20.9%
ROE32.9%77.8%
Long-term debt / equity0.48×1.54×
Market cap$653.54B$1.03T
P/E30.9×38.9×

Fundamentals are from each company’s SEC filings (JNJ FY2025, LLY FY2025). ROE is net income over fiscal-year-end equity; long-term debt / equity counts non-current term debt only. P/E and market cap are derived from stored market prices, last retrieved on a rolling basis and typically within the past week.

Five-year trend (as reported)

RevenueFY2021FY2022FY2023FY2024FY2025
JNJ$78.74B$79.99B$85.16B$88.82B$94.19B
LLY$28.32B$28.54B$34.12B$45.04B$65.18B
Net incomeFY2021FY2022FY2023FY2024FY2025
JNJ$20.88B$17.94B$35.15B$14.07B$26.80B
LLY$5.58B$6.24B$5.24B$10.59B$20.64B
Operating marginFY2021FY2022FY2023FY2024FY2025
JNJ
LLY

Peer standing

Where each company ranks among the 198 pharmaceutical companies, on the same scale. Each figure is ranked only against peers that report it. Percentiles describe position in the distribution, not a rating.

MetricJNJLLY
Gross margin
67.9%51st percentile of 69
83.0%82nd percentile of 69
Net margin
28.5%83rd percentile of 122
31.7%86th percentile of 122
Revenue growth (YoY)
+6.0%43rd percentile of 187
+44.7%72nd percentile of 187
ROE
32.9%90th percentile of 167
77.8%99th percentile of 167
P/E
30.9×68th percentile of 60
38.9×78th percentile of 60
Long-term debt / equity
0.48×48th percentile of 64
1.54×89th percentile of 64
Short interest (days to cover)
3.33d28th percentile of 197
2.11d18th percentile of 197

Short interest

FINRA settlement dataJNJLLY
Shares sold short21.6M6.6M
Change vs prior settlement-15.0%-28.0%
Days to cover3.332.11
As of settlement2026-08-142026-08-14

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data; republishing or redistributing it is not permitted. Not presented as a percentage of float. No FINRA endorsement of this product is implied.

Insider activity (last 90 days)

Form 4 activity (codes P/S)JNJLLY
Buys00
Sells9 ($61.0M)4 ($18.8M)

Non-derivative purchases (code P) and sales (code S) reported on SEC Form 4, which may be open-market or private (grants, exercises and tax withholding excluded). For context, about 15% of covered companies saw any reported insider purchase (code P) in a 90-day window.

Held by the same investors

9 tracked 13F managers hold both Johnson & Johnson and ELI LILLY as of their latest quarterly filings: AQR Capital Management, Bridgewater Associates, Citadel Advisors, D. E. Shaw, Dodge & Cox, Gotham Asset Management, Millennium Management, Soros Fund Management, Two Sigma Investments. See which superinvestors hold your own portfolio with the smart money checker.

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Data sourced from SEC EDGAR. Figures are as-reported and may be unaudited or restated; verify against the source filings before relying on them. Comparisons are descriptive (higher or lower on a reported figure), not a rating or a recommendation. Informational only. Not investment advice.