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AbbVie vs ELI LILLY (ABBV vs LLY)

Side by side from their SEC filings: revenue, margins, growth, returns and valuation, plus short interest, insider activity and institutional ownership.

ELI LILLY is the larger company by revenue ($65.2B vs $61.2B) and market value ($1.1T vs $438.3B). ELI LILLY has grown revenue faster over the last 4 fiscal years (+130.2% cumulative vs +8.8%). ELI LILLY trades at the lower trailing P/E (42.0x vs 122.2x).

About AbbVie

AbbVie Inc. is a global biopharmaceutical company that researches, develops, manufactures, and markets advanced therapies for complex and serious diseases. Its product portfolio includes treatments in immunology, neuroscience, and oncology, such as Skyrizi and Rinvoq for autoimmune diseases, Botox Therapeutic and Vraylar for neurological conditions, and Imbruvica and Venclexta for blood cancers. AbbVie serves patients worldwide across North America, the European Union, Japan, and other markets.

About ELI LILLY

Eli Lilly and Company discovers, develops, manufactures, and markets human pharmaceutical products worldwide. Its main products include treatments for diabetes, oncology, immunology, and neuroscience conditions. The company serves healthcare providers, wholesalers, pharmacies, hospitals, and patients in approximately 90 countries.

Head to head (ABBV FY2025 vs LLY FY2025)

MetricABBVFY2025LLYFY2025
Revenue$61.16B$65.18B
Revenue growth (YoY)8.6%44.7%
Gross margin70.2%83.0%
Operating margin24.6%
Net margin6.9%31.7%
Net income$4.23B$20.64B
Diluted EPS$2.36$22.95
FCF margin29.1%
ROE77.8%
Debt / equity1.5×
Market cap$438.31B$1.05T
P/E (TTM)122.2×42.0×

Fundamentals are from each company’s SEC filings (ABBV FY2025, LLY FY2025). P/E and market cap are derived from recent market prices and update daily.

Five-year trend (as reported)

RevenueFY2021FY2022FY2023FY2024FY2025
ABBV$56.20B$58.05B$54.32B$56.33B$61.16B
LLY$28.32B$28.54B$34.12B$45.04B$65.18B
Net incomeFY2021FY2022FY2023FY2024FY2025
ABBV$11.54B$11.84B$4.86B$4.28B$4.23B
LLY$5.58B$6.24B$5.24B$10.59B$20.64B
Operating marginFY2021FY2022FY2023FY2024FY2025
ABBV31.9%31.2%23.5%16.2%24.6%
LLY

Peer standing

Where each company ranks among the 198 pharmaceutical companies, on the same scale. Each figure is ranked only against peers that report it. Percentiles describe position in the distribution, not a rating.

MetricABBVLLY
Gross margin
70.2%55th percentile of 68
83.0%82nd percentile of 68
Net margin
6.9%62nd percentile of 121
31.7%86th percentile of 121
Revenue growth (YoY)
+8.6%47th percentile of 186
+44.7%72nd percentile of 186
P/E (TTM)
122.2×93rd percentile of 61
42.0×80th percentile of 61
Short interest (days to cover)
1.75d15th percentile of 197
2.58d24th percentile of 197

Short interest

FINRA settlement dataABBVLLY
Shares sold short21.9M9.4M
Change vs prior settlement-6.6%-3.2%
Days to cover1.752.58
As of settlement2026-06-302026-06-30

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data; republishing or redistributing it is not permitted. Not presented as a percentage of float. No FINRA endorsement of this product is implied.

Insider activity (last 90 days)

Form 4 open-market activityABBVLLY
Buys0
Sells3 ($18.6M)

Open-market purchases and sales reported on SEC Form 4 (grants, exercises and tax withholding excluded). For context, about 16% of covered companies saw any open-market insider buy in a 90-day window.

Held by the same investors

9 tracked 13F managers hold both AbbVie and ELI LILLY as of their latest quarterly filings: AQR Capital Management, Bridgewater Associates, Citadel Advisors, D. E. Shaw, Dodge & Cox, Gotham Asset Management, Harris Associates (Oakmark), Millennium Management, Two Sigma Investments. See which superinvestors hold your own portfolio with the smart money checker.

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Data sourced from SEC EDGAR (public domain). Figures are as-reported and may be unaudited or restated; verify against the source filings before relying on them. Comparisons are descriptive (higher or lower on a reported figure), not a rating or a recommendation. Informational only. Not investment advice.