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Nasdaq · Healthcare

Schrodinger, Inc. (SDGR)

As-reported financials and SEC filings for Schrodinger, Inc. The latest annual period is FY2025. The latest reported quarter is Q2 FY2026. Financial statements come straight from the company’s EDGAR filings; valuation figures such as P/E and market cap use market data.

About Schrodinger, Inc.

Schrödinger, Inc. provides a physics-based computational platform that accelerates the discovery and design of novel molecules for drug development and materials science applications. The company licenses its software to biopharmaceutical and industrial companies, academic institutions, and government laboratories worldwide. Schrödinger also conducts proprietary and collaborative drug discovery programs, advancing multiple candidates through preclinical and clinical development.

Snapshot

Revenue
$255.9M
Revenue growth (YoY)
23.3%
Net income
$-103.3M
Diluted EPS
$-1.41
Gross margin
55.7%
Operating margin
-65.2%
Net margin
-40.4%
FCF margin
4.9%
ROE
-28.4%
net income / fiscal-year-end equity
P/E
trailing when available, otherwise FY EPS
Market cap
$1.56B
Long-term debt / equity
non-current term debt only

Fundamentals are from SEC filings for FY2025, the latest annual period (ended December 31, 2025). P/E and market cap are derived from stored market prices, last retrieved on a rolling basis and typically within the past week.

What changed at Schrodinger

  • Revenue grew 23.3% to $256M in FY2025, after a 4.2% decline the year before.
  • Operating margin is -65.2% in FY2025, +15.6 pp against -80.8% in FY2021.
  • Most recent quarter Q2 FY2026: revenue $59M, up 7.5% from Q2 FY2025.
  • Free cash flow was $12M in FY2025, 4.9% of revenue.
  • Net loss narrowed to $103M in FY2025, from $187M in FY2024.

Computed from the as-reported figures in the statements below. A change we cannot state from filed figures is left out rather than estimated.

Peer comparison

Where Schrodinger’s fundamentals sit among the 198 pharmaceutical companies. Each figure is ranked only against peers that report it, from lowest (left) to highest (right).

Gross margin55.7%
37th percentile of 69
Operating margin-65.2%
11th percentile of 113
Net margin-40.4%
16th percentile of 122
FCF margin4.9%
52nd percentile of 110
Revenue growth (YoY)+23.3%
64th percentile of 187
ROE-28.4%
44th percentile of 167
Short interest8.42d
65th percentile of 197

Schrodinger’s operating margin of -65.2% ranks in the 11th percentile of the 113 pharmaceutical companies reporting it.

No reported insider purchases (code P) in the last 90 days; 1 insider sale totaling $13,647. For context, about 15% of companies in the universe saw any reported insider purchase (code P) in the same window. Browse insider activity →

Percentiles describe where a figure sits among industry peers reporting it (100th = highest). They are position within a peer group, not a rating, and not investment advice. Short interest ranking uses days to cover from FINRA Consolidated Short Interest data; FINRA is the owner and source of that data, included at no additional charge.

Institutional ownership

Held by 2 of the superinvestors we track (plus 3 quant / multi-strat books), based on each investor’s most recent 13F; periods vary by investor (newest: Q2 2026).

Conviction investors
2
+3 quant / multi-strat
Initiated / added
3
0 new, 3 added
Reduced / exited
4
1 trimmed, 3 exited
Combined position
$195.0M
reported long value
InvestorAs ofPosition valueSharesChange
Gates Foundation TrustQ2 2026$113.5M7.0MHeld
ARK Investment ManagementQ2 2026$35.0M2.2MAdded
AQR Capital ManagementquantQ2 2026$31.8M2.0MAdded
Citadel AdvisorsquantQ2 2026$14.6M895.8KAdded
Two Sigma InvestmentsquantQ2 2026$202,29612.4KReduced

No longer held by: D. E. Shaw (as of Q2 2026), Gotham Asset Management (as of Q2 2026), Millennium Management (as of Q2 2026)

From quarterly Form 13F filings, which can be up to 45 days delayed. Long US-listed positions only: excludes short positions, options, cash, bonds, and non-US holdings, so this is not a manager’s complete portfolio. Counts are of the investors we track, not all institutions. Not investment advice.

Recent insider activity

Non-derivative buys and sells (codes P/S) reported by officers, directors and 10% owners on SEC Form 4.

Buys (90d)
0
code P
Bought (90d)
code P value
Sells (90d)
1
$14K
Reported activity
Net selling
by $ value, 90d
Trade dateInsiderTypeSharesPriceValue
2026-07-16
filed 2026-07-17
Jain RachitEVP & CFOSell875$15.60$14K
2026-04-17
Farid RamyPresident & CEOSell43.0K$12.21$525K
2026-04-16
filed 2026-04-17
Farid RamyPresident & CEOSell43.0K$12.33$530K
2026-04-16
filed 2026-04-17
Jain RachitEVP & CFOSell844$12.75$11K

Reported non-derivative purchases and sales (codes P/S) — which may be open-market or private; excludes option exercises, grants, and shares withheld for taxes. Dates shown are the trade date; a Form 4 can be filed days to years later. A sale can be routine (e.g. a pre-set 10b5-1 plan), so read individual transactions in context. From SEC Form 4. Not investment advice.

Short interest

Total shares sold short as of each twice-monthly FINRA settlement. Rising short interest means more investors are positioned against the stock; days to cover estimates how many trading days of average volume that position represents.

Shares short
11.4M
settled 2026-08-14
Change vs prior
+3.8%
vs previous settlement
Days to cover
8.42
at avg daily volume
Avg daily volume
1.4M
FINRA reported
SettlementShares shortChangeDays to cover
2026-08-1411.4M+3.8%8.42
2026-07-3111.0M+4.0%12.83
2026-07-1510.6M+0.7%9.75
2026-06-3010.5M+4.9%6.02
2026-06-1510.0M-3.9%7.64
2026-05-2910.4M+1.5%7.92
2026-05-1510.3M-1.1%7.05
2026-04-3010.4M-4.9%6.24

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data, which is included at no additional charge for your own personal or professional use; republishing or redistributing it is not permitted. Settlement dates are shown; FINRA publishes each settlement about nine business days later, so the latest figure can be two to four weeks old. Not presented as a percentage of float. No FINRA endorsement of this product is implied. Not investment advice.

Income statement (as reported)

 FY2025FY2024FY2023FY2022FY2021
Revenue$255.9M$207.5M$216.7M$181.0M$137.9M
Gross profit$142.6M$132.1M$140.7M$101.0M$65.6M
Operating income$-166.9M$-209.3M$-177.4M$-146.8M$-111.4M
Net income$-103.3M$-187.1M$40.7M$-149.2M$-100.4M
Diluted EPS$-1.41$-2.57$0.54$-2.10$-1.42

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Balance sheet (as reported)

 FY2025FY2024FY2023FY2022FY2021
Cash and equivalents$230.5M$147.3M$155.3M$90.5M$120.3M
Current assets$519.3M$635.0M$567.8M$534.0M$625.1M
Total assets$726.2M$823.2M$803.0M$688.6M$756.5M
Current liabilities$189.1M$191.7M$133.7M$108.8M$91.2M
Long-term debt
Total liabilities$362.1M$401.8M$254.4M$240.7M$199.4M
Total equity$364.1M$421.4M$548.6M$447.9M$557.1M

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Cash flow (as reported)

 FY2025FY2024FY2023FY2022FY2021
Operating cash flow$13.9M$-157.4M$-136.7M$-119.7M$-70.7M
Capital expenditure$1.4M$7.3M$13.4M$8.0M$7.2M
Free cash flow$12.5M$-164.7M$-150.1M$-127.7M$-77.8M

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Quarterly trend (as reported)

QuarterRevenueRevenue YoYNet incomeDiluted EPS
Q2 FY2026$58.9M7.5%$6.0M$0.08
Q1 FY2026$58.6M-1.6%$-60.0M$-0.81
Q4 FY2025$87.2M-1.2%$32.5M$0.44
Q3 FY2025$54.3M53.9%$-32.8M$-0.45
Q2 FY2025$54.8M15.7%$-43.2M$-0.59
Q1 FY2025$59.6M62.7%$-59.8M$-0.82
Q4 FY2024$88.3M19.1%$-40.2M$-0.55
Q3 FY2024$35.3M-17.1%$-38.1M$-0.52

Latest 8 reported quarters, from company XBRL filings on SEC EDGAR.

Company facts

ExchangeNasdaq
SectorHealthcare
SIC industryPharmaceutical Preparations
Latest annual periodFY2025 (ended December 31, 2025)
Latest reported quarterQ2 FY2026 (ended June 30, 2026)
Oldest indexed filing2010
SEC CIK1490978

Selected SEC filings

10-Q2026-08-05
View on EDGAR →
10-Q2026-05-05
View on EDGAR →
8-K2026-08-05
View on EDGAR →
8-K2026-06-29
View on EDGAR →
8-K2026-06-23
View on EDGAR →
8-K2026-06-08
View on EDGAR →

Largest pharmaceutical peers

All pharmaceutical stocksAll Healthcare companies →

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Data sourced from SEC EDGAR. Figures are as-reported and may be unaudited or restated; verify against the source filing before relying on them. Informational only. Not investment advice.