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Nasdaq · Healthcare

Mirum Pharmaceuticals, Inc. (MIRM)

As-reported financials and SEC filings for Mirum Pharmaceuticals, Inc. The latest annual period is FY2025. The latest reported quarter is Q2 FY2026. Financial statements come straight from the company’s EDGAR filings; valuation figures such as P/E and market cap use market data.

About Mirum Pharmaceuticals, Inc.

Mirum Pharmaceuticals, Inc. is a biopharmaceutical company focused on developing and commercializing treatments for rare diseases. It markets three approved medicines: Livmarli for cholestatic pruritus in patients with Alagille syndrome and progressive familial intrahepatic cholestasis, Cholbam for bile acid synthesis disorders and peroxisomal disorders, and Ctexli for cerebrotendinous xanthomatosis. The company also develops product candidates for cholestatic liver diseases, chronic hepatitis D virus infection, and fragile X syndrome.

Snapshot

Revenue
$521.3M
Revenue growth (YoY)
54.7%
Net income
$-23.4M
Diluted EPS
$-0.47
Gross margin
Operating margin
-4.2%
Net margin
-4.5%
FCF margin
10.5%
ROE
-7.4%
net income / fiscal-year-end equity
P/E
trailing when available, otherwise FY EPS
Market cap
$5.98B
Long-term debt / equity
non-current term debt only

Fundamentals are from SEC filings for FY2025, the latest annual period (ended December 31, 2025). P/E and market cap are derived from stored market prices, last retrieved on a rolling basis and typically within the past week.

What changed at Mirum Pharmaceuticals

  • Revenue grew 54.7% to $521M in FY2025, slower than the 80.8% the year before.
  • Operating margin is -4.2% in FY2025, +901.9 pp against -906.1% in FY2021.
  • Most recent quarter Q2 FY2026: revenue $176M, up 37.9% from Q2 FY2025.
  • Free cash flow was $55M in FY2025, 10.5% of revenue.
  • Net loss narrowed to $23M in FY2025, from $88M in FY2024.

Computed from the as-reported figures in the statements below. A change we cannot state from filed figures is left out rather than estimated.

Peer comparison

Where Mirum Pharmaceuticals’s fundamentals sit among the 198 pharmaceutical companies. Each figure is ranked only against peers that report it, from lowest (left) to highest (right).

Operating margin-4.2%
46th percentile of 113
Net margin-4.5%
45th percentile of 122
FCF margin10.5%
61st percentile of 110
Revenue growth (YoY)+54.7%
75th percentile of 187
ROE-7.4%
63rd percentile of 167
Short interest7.27d
59th percentile of 197

No reported insider purchases (code P) in the last 90 days; 19 insider sales totaling $10.9M. For context, about 14% of companies in the universe saw any reported insider purchase (code P) in the same window. Browse insider activity →

Percentiles describe where a figure sits among industry peers reporting it (100th = highest). They are position within a peer group, not a rating, and not investment advice. Short interest ranking uses days to cover from FINRA Consolidated Short Interest data; FINRA is the owner and source of that data, included at no additional charge.

Institutional ownership

Held by 2 of the superinvestors we track (plus 5 quant / multi-strat books), based on each investor’s most recent 13F; periods vary by investor (newest: Q2 2026).

Conviction investors
2
+5 quant / multi-strat
Initiated / added
1
0 new, 1 added
Reduced / exited
8
6 trimmed, 2 exited
Combined position
$153.2M
reported long value
InvestorAs ofPosition valueSharesChange
Two Sigma InvestmentsquantQ2 2026$80.8M690.3KReduced
Renaissance TechnologiesquantQ2 2026$51.8M442.2KReduced
Millennium ManagementquantQ2 2026$11.3M96.2KReduced
AQR Capital ManagementquantQ2 2026$3.4M28.6KReduced
D. E. ShawquantQ2 2026$3.3M27.9KReduced
Polen Capital ManagementQ2 2026$2.4M20.9KAdded
Gotham Asset ManagementQ2 2026$279,2122.4KReduced

No longer held by: Citadel Advisors (as of Q2 2026), Point72 Asset Management (as of Q2 2026)

From quarterly Form 13F filings, which can be up to 45 days delayed. Long US-listed positions only: excludes short positions, options, cash, bonds, and non-US holdings, so this is not a manager’s complete portfolio. Counts are of the investors we track, not all institutions. Not investment advice.

Recent insider activity

Non-derivative buys and sells (codes P/S) reported by officers, directors and 10% owners on SEC Form 4.

Buys (90d)
0
code P
Bought (90d)
code P value
Sells (90d)
19
$10.9M
Reported activity
Net selling
by $ value, 90d
Trade dateInsiderTypeSharesPriceValue
2026-08-18
filed 2026-08-19
Howe JolandaSVP, GLOBAL CONTROLLERSell40.0K$100.00$4.0M
2026-08-11
filed 2026-08-12
BJERKHOLT ERICCHIEF FINANCIAL OFFICERSell6.0K$99.90$600K
2026-08-10
filed 2026-08-11
Peetz ChristopherCHIEF EXECUTIVE OFFICERSell11.7K$98.51$1.2M
2026-08-10
filed 2026-08-11
Peetz ChristopherCHIEF EXECUTIVE OFFICERSell6.0K$99.25$597K
2026-08-10
filed 2026-08-11
Peetz ChristopherCHIEF EXECUTIVE OFFICERSell2.3K$100.14$230K
2026-08-03
filed 2026-08-05
Howe JolandaSVP, GLOBAL CONTROLLERSell1.8K$105.29$194K
2026-07-06
filed 2026-07-08
Peetz ChristopherCHIEF EXECUTIVE OFFICERSell12.1K$121.65$1.5M
2026-07-06
filed 2026-07-08
Peetz ChristopherCHIEF EXECUTIVE OFFICERSell4.2K$122.34$512K
2026-07-06
filed 2026-07-08
BJERKHOLT ERICCHIEF FINANCIAL OFFICERSell3.1K$121.67$380K
2026-07-06
filed 2026-07-08
Peetz ChristopherCHIEF EXECUTIVE OFFICERSell2.0K$123.74$244K
2026-07-06
filed 2026-07-08
Peetz ChristopherCHIEF EXECUTIVE OFFICERSell1.7K$124.79$213K
2026-07-06
filed 2026-07-08
BJERKHOLT ERICCHIEF FINANCIAL OFFICERSell1.0K$122.43$128K

Reported non-derivative purchases and sales (codes P/S) — which may be open-market or private; excludes option exercises, grants, and shares withheld for taxes. Dates shown are the trade date; a Form 4 can be filed days to years later. A sale can be routine (e.g. a pre-set 10b5-1 plan), so read individual transactions in context. From SEC Form 4. Not investment advice.

Short interest

Total shares sold short as of each twice-monthly FINRA settlement. Rising short interest means more investors are positioned against the stock; days to cover estimates how many trading days of average volume that position represents.

Shares short
6.5M
settled 2026-08-14
Change vs prior
-4.9%
vs previous settlement
Days to cover
7.27
at avg daily volume
Avg daily volume
892.9K
FINRA reported
SettlementShares shortChangeDays to cover
2026-08-146.5M-4.9%7.27
2026-07-316.8M-6.2%12.05
2026-07-157.3M-2.8%10.59
2026-06-307.5M+8.3%5.02
2026-06-156.9M+5.3%11.24
2026-05-296.6M-19.9%7.92
2026-05-158.2M-2.6%4.83
2026-04-308.4M+2.4%14.67

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data, which is included at no additional charge for your own personal or professional use; republishing or redistributing it is not permitted. Settlement dates are shown; FINRA publishes each settlement about nine business days later, so the latest figure can be two to four weeks old. Not presented as a percentage of float. No FINRA endorsement of this product is implied. Not investment advice.

Income statement (as reported)

 FY2025FY2024FY2023FY2022FY2021
Revenue$521.3M$336.9M$186.4M$77.1M$19.1M
Gross profit
Operating income$-22.1M$-87.6M$-109.2M$-131.2M$-173.4M
Net income$-23.4M$-87.9M$-163.4M$-135.7M$-84.0M
Diluted EPS$-0.47$-1.85$-4.00$-4.02$-2.77

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Balance sheet (as reported)

 FY2025FY2024FY2023FY2022FY2021
Cash and equivalents$296.7M$222.5M$286.3M$28.0M$31.3M
Current assets$549.7M$392.8M$387.5M$190.2M$166.6M
Total assets$842.8M$670.8M$646.6M$352.9M$294.7M
Current liabilities$205.8M$126.6M$87.1M$64.7M$42.6M
Long-term debt
Total liabilities$528.1M$445.1M$398.0M$210.9M$174.4M
Total equity$314.7M$225.6M$248.7M$142.0M$120.2M

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Cash flow (as reported)

 FY2025FY2024FY2023FY2022FY2021
Operating cash flow$55.8M$10.3M$-70.9M$-120.1M$-132.8M
Capital expenditure$954,000$993,000$109,000$278,000$24,000
Free cash flow$54.9M$9.3M$-71.1M$-120.4M$-132.8M

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Quarterly trend (as reported)

QuarterRevenueRevenue YoYNet incomeDiluted EPS
Q2 FY2026$176.2M37.9%$-67.2M$-1.06
Q1 FY2026$159.9M43.3%$-790.2M$-13.43
Q4 FY2025$148.9M49.8%$-5.7M$-0.11
Q3 FY2025$133.0M47.2%$2.9M$0.05
Q2 FY2025$127.8M64.1%$-5.9M$-0.12
Q1 FY2025$111.6M61.2%$-14.7M$-0.30
Q4 FY2024$99.4M42.9%$-23.8M$-0.49
Q3 FY2024$90.4M89.4%$-14.2M$-0.30

Latest 8 reported quarters, from company XBRL filings on SEC EDGAR.

Company facts

ExchangeNasdaq
SectorHealthcare
SIC industryPharmaceutical Preparations
Latest annual periodFY2025 (ended December 31, 2025)
Latest reported quarterQ2 FY2026 (ended June 30, 2026)
Oldest indexed filing2018
SEC CIK1759425

Selected SEC filings

10-Q2026-08-05
View on EDGAR →
10-Q2026-05-06
View on EDGAR →
8-K2026-08-05
View on EDGAR →
8-K2026-06-18
View on EDGAR →
8-K2026-05-18
View on EDGAR →
8-K2026-05-06
View on EDGAR →

Largest pharmaceutical peers

All pharmaceutical stocksAll Healthcare companies →

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Data sourced from SEC EDGAR. Figures are as-reported and may be unaudited or restated; verify against the source filing before relying on them. Informational only. Not investment advice.