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Nasdaq · Healthcare

Cryoport, Inc. (CYRX)

As-reported financials and SEC filings for Cryoport, Inc. The latest annual period is FY2025. The latest reported quarter is Q2 FY2026. Financial statements come straight from the company’s EDGAR filings; valuation figures such as P/E and market cap use market data.

About Cryoport, Inc.

Cryoport, Inc. provides integrated temperature-controlled supply chain solutions for the life sciences industry, focusing on cell and gene therapy markets. The company offers services including advanced logistics, biostorage, cryopreservation, and cryogenic systems manufacturing to support the storage, handling, and delivery of temperature-sensitive biological materials. Cryoport serves biopharmaceutical companies, academic institutions, research organizations, and government agencies globally.

Snapshot

Revenue
$176.2M
Revenue growth (YoY)
12.4%
Net income
$78.3M
Diluted EPS
$1.40
Gross margin
47.1%
Operating margin
-20.9%
Net margin
44.4%
FCF margin
-14.2%
ROE
15.6%
net income / fiscal-year-end equity
P/E
n/m
not meaningful: a reported loss in the fiscal year or the trailing twelve months
Market cap
$842.8M
Long-term debt / equity
—
non-current term debt only

Fundamentals are from SEC filings for FY2025, the latest annual period (ended December 31, 2025). P/E and market cap are derived from stored market prices, last retrieved on a rolling basis and typically within the past week.

What changed at Cryoport

  • Revenue grew 12.4% to $176M in FY2025, after a 7.1% decline the year before.
  • Operating margin is -20.9% in FY2025, -12.9 pp against -8.0% in FY2021.
  • Most recent quarter Q2 FY2026: revenue $49M, up 7.7% from Q2 FY2025.
  • Free cash flow was negative $25M in FY2025.
  • Net income turned positive at $78M in FY2025, from a $115M loss in FY2024.

Computed from the as-reported figures in the statements below. A change we cannot state from filed figures is left out rather than estimated.

Peer comparison

Where Cryoport’s fundamentals sit among the 198 pharmaceutical companies. Each figure is ranked only against peers that report it, from lowest (left) to highest (right).

Gross margin47.1%
22nd percentile of 69
Operating margin-20.9%
27th percentile of 112
Net margin44.4%
93rd percentile of 121
FCF margin-14.2%
27th percentile of 110
Revenue growth (YoY)+12.4%
53rd percentile of 188
ROE15.6%
83rd percentile of 167
Short interest3.38d
24th percentile of 197

Cryoport’s net margin of 44.4% ranks in the 93rd percentile of the 121 pharmaceutical companies reporting it.

No reported insider purchases (code P) in the last 90 days; 1 insider sale totaling $429,385. For context, about 15% of companies in the universe saw any reported insider purchase (code P) in the same window. Browse insider activity →

Percentiles describe where a figure sits among industry peers reporting it (100th = highest). They are position within a peer group, not a rating, and not investment advice. Short interest ranking uses days to cover from FINRA Consolidated Short Interest data; FINRA is the owner and source of that data, included at no additional charge.

Institutional ownership

Held by 1 of the superinvestors we track (plus 6 quant / multi-strat books), based on each investor’s most recent 13F; periods vary by investor (newest: Q2 2026).

Conviction investors
1
+6 quant / multi-strat
Initiated / added
5
1 new, 4 added
Reduced / exited
2
2 trimmed, 0 exited
Combined position
$69.4M
reported long value
InvestorAs ofPosition valueSharesChange
Millennium ManagementquantQ2 2026$27.1M1.7MReduced
First Eagle Investment ManagementQ2 2026$20.0M1.3MAdded
D. E. ShawquantQ2 2026$7.5M479.6KAdded
AQR Capital ManagementquantQ2 2026$6.3M400.4KAdded
Renaissance TechnologiesquantQ2 2026$5.8M372.4KAdded
Citadel AdvisorsquantQ2 2026$2.4M155.8KReduced
Two Sigma InvestmentsquantQ2 2026$225,20114.3KNew

From quarterly Form 13F filings, which can be up to 45 days delayed. Long US-listed positions only: excludes short positions, options, cash, bonds, and non-US holdings, so this is not a manager’s complete portfolio. Counts are of the investors we track, not all institutions. Not investment advice.

Recent insider activity

Non-derivative buys and sells (codes P/S) reported by officers, directors and 10% owners on SEC Form 4.

Buys (90d)
0
code P
Bought (90d)
—
code P value
Sells (90d)
1
$429K
Reported activity
Net selling
by $ value, 90d
Trade dateInsiderTypeSharesPriceValue
2026-08-11
Jerrell SheltonPresident, CEOSell28.8K$14.91$429K
2026-06-11
filed 2026-06-12
Edward J. ZecchiniChief Digital and Tech OfficerSell33.6K$14.47$486K
2026-06-10
filed 2026-06-12
Edward J. ZecchiniChief Digital and Tech OfficerSell1.4K$15.23$21K
2026-06-08
Ramkumar MandalamDirectorSell23.2K$15.44$358K
2026-06-04
filed 2026-06-08
Robert StefanovichChief Financial OfficerSell169.4K$16.27$2.8M

Reported non-derivative purchases and sales (codes P/S), which may be open-market or private. Excludes option exercises, grants, and shares withheld for taxes. Dates shown are the trade date; a Form 4 can be filed days to years later. A sale can be routine (e.g. a pre-set 10b5-1 plan), so read individual transactions in context. From SEC Form 4. Not investment advice.

Short interest

Total shares sold short as of each twice-monthly FINRA settlement. Rising short interest means more investors are positioned against the stock; days to cover estimates how many trading days of average volume that position represents.

Shares short
2.4M
settled 2026-09-30
Change vs prior
-15.2%
vs previous settlement
Days to cover
3.38
at avg daily volume
Avg daily volume
698.4K
FINRA reported
SettlementShares shortChangeDays to cover
2026-09-302.4M-15.2%3.38
2026-09-152.8M+2.7%5.83
2026-08-312.7M+7.9%4.85
2026-08-142.5M+0.6%4.65
2026-07-312.5M-0.8%4.04
2026-07-152.5M+15.7%3.68
2026-06-302.2M-0.9%2.57
2026-06-152.2M-5.1%2.26

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data, which is included at no additional charge for your own personal or professional use; republishing or redistributing it is not permitted. Settlement dates are shown; FINRA publishes each settlement about nine business days later, so the latest figure can be two to four weeks old. Not presented as a percentage of float. No FINRA endorsement of this product is implied. Not investment advice.

Income statement (as reported)

 FY2025FY2024FY2023FY2022FY2021
Revenue$176.2M$156.8M$168.7M$237.3M$222.6M
Gross profit
Operating income$-36.8M$-121.7M$-100.5M$-31.9M$-17.8M
Net income$78.3M$-114.8M$-99.6M$-37.3M$-275.5M
Diluted EPS$1.40$-2.49$-2.21$-0.93$-6.18

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (tap or hover a figure to see how it was calculated or what was filed). Full details: where the numbers come from.

Balance sheet (as reported)

 FY2025FY2024FY2023FY2022FY2021
Cash and equivalents$250.5M$34.1M$35.2M$29.2M$139.1M
Current assets$476.2M$341.6M$535.1M$604.2M$693.5M
Total assets$765.0M$703.5M$957.7M$1.04B$1.11B
Current liabilities$219.0M$64.6M$45.6M$40.9M$42.6M
Long-term debt—————
Total liabilities$262.4M$301.6M$468.7M$482.9M$471.1M
Total equity$502.6M$401.9M$489.0M$555.8M$641.8M

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (tap or hover a figure to see how it was calculated or what was filed). Full details: where the numbers come from.

Cash flow (as reported)

 FY2025FY2024FY2023FY2022FY2021
Operating cash flow$-8.6M$-16.3M$-757,000$-1.9M$8.1M
Capital expenditure$16.4M$17.3M$38.8M$22.1M$23.9M
Free cash flow

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (tap or hover a figure to see how it was calculated or what was filed). Full details: where the numbers come from.

Quarterly trend

QuarterRevenueRevenue YoYNet incomeDiluted EPS
Q2 FY2026$49.0M7.7%$-8.3M$-0.20
Q1 FY2026$47.8M16.5%$-10.5M$-0.25
Q4 FY20259.6%
Q3 FY2025$44.2M15.4%$-6.9M$-0.18
Q2 FY2025$45.5M14.5%$108.9M$2.13
Q1 FY2025$41.0M10.1%$-12.0M$-0.28
Q4 FY2024—
Q3 FY2024$38.3M-31.8%$805,000—

Latest 8 quarters, from company XBRL filings on SEC EDGAR. A dotted underline marks a fourth-quarter figure we calculated from the full year and the first nine months. Revenue YoY is our calculation too: each quarter against the same quarter a year earlier.

Company facts

ExchangeNasdaq
SectorHealthcare
SIC industryPharmaceutical Preparations
Latest annual periodFY2025 (ended December 31, 2025)
Latest reported quarterQ2 FY2026 (ended June 30, 2026)
Oldest indexed filing2008
SEC CIK1124524

Selected SEC filings

10-K2026-03-05
View on EDGAR →
10-Q2026-08-06
View on EDGAR →
10-Q2026-05-05
View on EDGAR →
10-Q2025-11-06
View on EDGAR →
8-K2026-08-06
View on EDGAR →
8-K2026-06-09
View on EDGAR →
8-K2026-05-04
View on EDGAR →
8-K2026-03-03
View on EDGAR →

Largest pharmaceutical peers

All pharmaceutical stocks →All Healthcare companies →

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Data sourced from SEC EDGAR. Figures are as-reported and may be unaudited or restated; verify against the source filing before relying on them. Informational only. Not investment advice.