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Nasdaq · Healthcare

REPLIGEN CORP (RGEN)

As-reported financials and SEC filings for REPLIGEN CORP. The latest annual period is FY2025. The latest reported quarter is Q2 FY2026. Financial statements come straight from the company’s EDGAR filings; valuation figures such as P/E and market cap use market data.

About REPLIGEN CORP

Repligen Corporation is a global life sciences company that develops and sells bioprocessing technologies and systems to improve the manufacturing of biological drugs. Its main products include filtration systems, chromatography columns, process analytics, and proteins, which serve global biopharmaceutical companies, contract development and manufacturing organizations, and other life science companies. The company offers solutions for both upstream and downstream processes in biologic drug production, including monoclonal antibodies, recombinant proteins, RNA therapeutics, vaccines, and cell and gene therapies.

Snapshot

Revenue
$738.3M
Revenue growth (YoY)
16.4%
Net income
$48.9M
Diluted EPS
$0.86
Gross margin
52.3%
Operating margin
7.5%
Net margin
6.6%
FCF margin
12.7%
ROE
2.3%
net income / fiscal-year-end equity
P/E
244.8×
trailing when available, otherwise FY EPS
Market cap
$9.95B
Long-term debt / equity
0.26×
non-current term debt only

Fundamentals are from SEC filings for FY2025, the latest annual period (ended December 31, 2025). P/E and market cap are derived from stored market prices, last retrieved on a rolling basis and typically within the past week.

What changed at Repligen

  • Revenue grew 16.4% to $738M in FY2025, faster than the 0.3% the year before.
  • Operating margin is 7.5% in FY2025, -17.5 pp against 24.9% in FY2021.
  • Most recent quarter Q2 FY2026: revenue $204M, up 11.9% from Q2 FY2025.
  • Free cash flow was $94M in FY2025, 12.7% of revenue.
  • Net income turned positive at $49M in FY2025, from a $26M loss in FY2024.

Computed from the as-reported figures in the statements below. A change we cannot state from filed figures is left out rather than estimated.

Peer comparison

Where Repligen’s fundamentals sit among the 71 biotech companies. Each figure is ranked only against peers that report it, from lowest (left) to highest (right).

Gross margin52.3%
23rd percentile of 14
Operating margin7.5%
50th percentile of 31
Net margin6.6%
48th percentile of 32
FCF margin12.7%
59th percentile of 28
Revenue growth (YoY)+16.4%
46th percentile of 64
ROE2.3%
73rd percentile of 61
P/E244.8×
Highest of 20
Long-term debt / equity0.26×
42nd percentile of 20
Short interest6.44d
44th percentile of 71

Repligen’s P/E of 244.8 is the highest of the 20 peers with a meaningful P/E.

No reported insider purchases (code P) in the last 90 days; 3 insider sales totaling $1.2M. For context, about 15% of companies in the universe saw any reported insider purchase (code P) in the same window. Browse insider activity →

Percentiles describe where a figure sits among industry peers reporting it (100th = highest). They are position within a peer group, not a rating, and not investment advice. Short interest ranking uses days to cover from FINRA Consolidated Short Interest data; FINRA is the owner and source of that data, included at no additional charge.

Institutional ownership

Held by 3 of the superinvestors we track (plus 5 quant / multi-strat books), based on each investor’s most recent 13F; periods vary by investor (newest: Q2 2026).

Conviction investors
3
+5 quant / multi-strat
Initiated / added
6
3 new, 3 added
Reduced / exited
3
2 trimmed, 1 exited
Combined position
$388.7M
reported long value
InvestorAs ofPosition valueSharesChange
Maverick CapitalQ2 2026$270.8M2.0MAdded
Citadel AdvisorsquantQ2 2026$51.3M376.3KReduced
Point72 Asset ManagementquantQ2 2026$22.7M166.2KReduced
Gotham Asset ManagementQ2 2026$19.5M142.6KAdded
D. E. ShawquantQ2 2026$11.4M83.3KNew
Duquesne Family OfficeQ2 2026$10.6M77.4KNew
Two Sigma InvestmentsquantQ2 2026$1.4M9.9KNew
AQR Capital ManagementquantQ2 2026$1.2M8.9KAdded

No longer held by: Millennium Management (as of Q2 2026)

From quarterly Form 13F filings, which can be up to 45 days delayed. Long US-listed positions only: excludes short positions, options, cash, bonds, and non-US holdings, so this is not a manager’s complete portfolio. Counts are of the investors we track, not all institutions. Not investment advice.

Recent insider activity

Non-derivative buys and sells (codes P/S) reported by officers, directors and 10% owners on SEC Form 4.

Buys (90d)
0
code P
Bought (90d)
code P value
Sells (90d)
3
$1.2M
Reported activity
Net selling
by $ value, 90d
Trade dateInsiderTypeSharesPriceValue
2026-08-20
filed 2026-08-21
Loeillot OlivierChief Executive OfficerSell5.4K$180.00$977K
2026-07-16
filed 2026-07-17
Garland Jason KCFOSell530$150.00$80K
2026-06-25
filed 2026-06-26
Garland Jason KCFOSell733$145.00$106K
2026-04-21
filed 2026-04-22
Loeillot OlivierChief Executive OfficerSell3.8K$140.00$536K

Reported non-derivative purchases and sales (codes P/S) — which may be open-market or private; excludes option exercises, grants, and shares withheld for taxes. Dates shown are the trade date; a Form 4 can be filed days to years later. A sale can be routine (e.g. a pre-set 10b5-1 plan), so read individual transactions in context. From SEC Form 4. Not investment advice.

Short interest

Total shares sold short as of each twice-monthly FINRA settlement. Rising short interest means more investors are positioned against the stock; days to cover estimates how many trading days of average volume that position represents.

Shares short
6.1M
settled 2026-08-14
Change vs prior
-0.8%
vs previous settlement
Days to cover
6.44
at avg daily volume
Avg daily volume
944.7K
FINRA reported
SettlementShares shortChangeDays to cover
2026-08-146.1M-0.8%6.44
2026-07-316.1M+5.5%3.93
2026-07-155.8M-3.9%7.93
2026-06-306.0M+5.6%4.65
2026-06-155.7M-4.0%6.36
2026-05-296.0M+4.7%4.89
2026-05-155.7M+3.5%3.87
2026-04-305.5M+0.3%4.98

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data, which is included at no additional charge for your own personal or professional use; republishing or redistributing it is not permitted. Settlement dates are shown; FINRA publishes each settlement about nine business days later, so the latest figure can be two to four weeks old. Not presented as a percentage of float. No FINRA endorsement of this product is implied. Not investment advice.

Income statement (as reported)

 FY2025FY2024FY2023FY2022FY2021
Revenue$738.3M$634.4M$632.4M$801.5M$670.5M
Gross profit$386.2M$274.6M$278.4M$455.7M$391.3M
Operating income$55.2M$-35.1M$47.7M$224.7M$167.2M
Net income$48.9M$-25.5M$35.6M$186.0M$128.3M
Diluted EPS$0.86$-0.46$0.63$3.24$2.24

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Balance sheet (as reported)

 FY2025FY2024FY2023FY2022FY2021
Cash and equivalents$566.0M$757.4M$751.3M$523.5M$603.8M
Current assets$1.14B$1.07B$1.11B$998.1M$931.7M
Total assets$2.95B$2.83B$2.83B$2.53B$2.36B
Current liabilities$135.8M$126.8M$164.9M$404.2M$375.3M
Long-term debt$542.2M$525.6M
Total liabilities$843.6M$856.9M$866.3M$620.9M$608.3M
Total equity$2.11B$1.97B$1.96B$1.91B$1.75B

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Cash flow (as reported)

 FY2025FY2024FY2023FY2022FY2021
Operating cash flow$117.4M$175.4M$113.9M$172.1M$119.0M
Capital expenditure$23.5M$25.7M$36.2M$84.8M$67.1M
Free cash flow$93.9M$149.7M$77.7M$87.2M$51.9M

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Quarterly trend (as reported)

QuarterRevenueRevenue YoYNet incomeDiluted EPS
Q2 FY2026$204.1M11.9%$5.0M$0.09
Q1 FY2026$194.3M14.8%$8.3M$0.15
Q4 FY2025$197.9M18.1%$13.3M
Q3 FY2025$188.8M21.9%$14.9M$0.26
Q2 FY2025$182.4M14.8%$14.9M$0.26
Q1 FY2025$169.2M10.4%$5.8M$0.10
Q4 FY2024$167.5M0.6%$-33.9M
Q3 FY2024$154.9M9.7%$-654,000$-0.01

Latest 8 reported quarters, from company XBRL filings on SEC EDGAR.

Company facts

ExchangeNasdaq
SectorHealthcare
SIC industryBiological Products, (No Diagnostic Substances)
Latest annual periodFY2025 (ended December 31, 2025)
Latest reported quarterQ2 FY2026 (ended June 30, 2026)
Oldest indexed filing2009
SEC CIK730272

Selected SEC filings

10-K2026-02-26
View on EDGAR →
10-Q2026-07-29
View on EDGAR →
10-Q2026-05-06
View on EDGAR →
8-K2026-07-28
View on EDGAR →
8-K2026-07-22
View on EDGAR →
8-K2026-05-15
View on EDGAR →
8-K2026-05-05
View on EDGAR →

Largest biotech peers

All biotech stocksAll Healthcare companies →

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Data sourced from SEC EDGAR. Figures are as-reported and may be unaudited or restated; verify against the source filing before relying on them. Informational only. Not investment advice.