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Nasdaq · Healthcare

LIGAND PHARMACEUTICALS INC (LGND)

As-reported financials and SEC filings for LIGAND PHARMACEUTICALS INC. The latest annual period is FY2025. The latest reported quarter is Q2 FY2026. Financial statements come straight from the company’s EDGAR filings; valuation figures such as P/E and market cap use market data.

About LIGAND PHARMACEUTICALS INC

Ligand Pharmaceuticals is a biopharmaceutical royalty company that invests in and licenses technologies to acquire royalty streams from mid- to late-stage development and commercial biopharmaceutical products. The company generates revenue primarily from royalties on sales of partner-commercialized products, as well as from sales and licensing fees related to its Captisol and NITRICIL platform technologies. Ligand serves biopharmaceutical partners by providing capital and structuring royalty interests while maintaining a lean operational infrastructure.

Snapshot

Revenue
$268.1M
Revenue growth (YoY)
60.4%
Net income
$124.5M
Diluted EPS
$6.13
Gross margin
Operating margin
15.3%
Net margin
46.4%
FCF margin
18.2%
ROE
12.2%
net income / fiscal-year-end equity
P/E
29.0×
trailing when available, otherwise FY EPS
Market cap
$5.74B
Long-term debt / equity
non-current term debt only

Fundamentals are from SEC filings for FY2025, the latest annual period (ended December 31, 2025). P/E and market cap are derived from stored market prices, last retrieved on a rolling basis and typically within the past week.

What changed at Ligand Pharmaceuticals

  • Revenue grew 60.4% to $268M in FY2025, faster than the 27.3% the year before.
  • Operating margin is 15.3% in FY2025, -27.7 pp against 43.0% in FY2021.
  • Most recent quarter Q2 FY2026: revenue $64M, up 33.7% from Q2 FY2025.
  • Free cash flow was $49M in FY2025, 18.2% of revenue.
  • Net income turned positive at $124M in FY2025, from a $4M loss in FY2024.

Computed from the as-reported figures in the statements below. A change we cannot state from filed figures is left out rather than estimated.

Peer comparison

Where Ligand Pharmaceuticals’s fundamentals sit among the 198 pharmaceutical companies. Each figure is ranked only against peers that report it, from lowest (left) to highest (right).

Operating margin15.3%
76th percentile of 113
Net margin46.4%
93rd percentile of 122
FCF margin18.2%
72nd percentile of 110
Revenue growth (YoY)+60.4%
76th percentile of 187
ROE12.2%
77th percentile of 167
P/E29.0×
66th percentile of 60
Short interest8.76d
66th percentile of 197

Ligand Pharmaceuticals’s net margin of 46.4% ranks in the 93rd percentile of the 122 pharmaceutical companies reporting it.

No reported insider purchases (code P) in the last 90 days; 29 insider sales totaling $18.9M. For context, about 15% of companies in the universe saw any reported insider purchase (code P) in the same window. Browse insider activity →

Percentiles describe where a figure sits among industry peers reporting it (100th = highest). They are position within a peer group, not a rating, and not investment advice. Short interest ranking uses days to cover from FINRA Consolidated Short Interest data; FINRA is the owner and source of that data, included at no additional charge.

Institutional ownership

Held by 1 of the superinvestors we track (plus 4 quant / multi-strat books), based on each investor’s most recent 13F; periods vary by investor (newest: Q2 2026).

Conviction investors
1
+4 quant / multi-strat
Initiated / added
3
2 new, 1 added
Reduced / exited
3
2 trimmed, 1 exited
Combined position
$29.5M
reported long value
InvestorAs ofPosition valueSharesChange
D. E. ShawquantQ2 2026$17.9M56.5KReduced
Two Sigma InvestmentsquantQ2 2026$6.0M18.8KNew
AQR Capital ManagementquantQ2 2026$3.3M10.4KAdded
Millennium ManagementquantQ2 2026$1.3M4.0KNew
Gotham Asset ManagementQ2 2026$1.1M3.6KReduced

No longer held by: Citadel Advisors (as of Q2 2026)

From quarterly Form 13F filings, which can be up to 45 days delayed. Long US-listed positions only: excludes short positions, options, cash, bonds, and non-US holdings, so this is not a manager’s complete portfolio. Counts are of the investors we track, not all institutions. Not investment advice.

Recent insider activity

Non-derivative buys and sells (codes P/S) reported by officers, directors and 10% owners on SEC Form 4.

Buys (90d)
0
code P
Bought (90d)
code P value
Sells (90d)
29
$18.9M
Reported activity
Net selling
by $ value, 90d
Trade dateInsiderTypeSharesPriceValue
2026-08-12
filed 2026-08-14
Espinoza OctavioChief Financial OfficerSell31.6K$292.06$9.2M
2026-08-12
filed 2026-08-14
Haas JasonDirectorSell7.1K$292.81$2.1M
2026-08-03
filed 2026-08-04
Reardon AndrewCLO & SecretarySell1.2K$287.77$349K
2026-08-03
filed 2026-08-04
Reardon AndrewCLO & SecretarySell1.0K$286.80$296K
2026-08-03
filed 2026-08-04
Reardon AndrewCLO & SecretarySell991$291.71$289K
2026-08-03
filed 2026-08-04
Reardon AndrewCLO & SecretarySell503$289.80$146K
2026-08-03
filed 2026-08-04
Reardon AndrewCLO & SecretarySell409$292.82$120K
2026-08-03
filed 2026-08-04
Reardon AndrewCLO & SecretarySell356$288.75$103K
2026-08-03
filed 2026-08-04
Reardon AndrewCLO & SecretarySell200$290.60$58K
2026-08-03
filed 2026-08-04
Reardon AndrewCLO & SecretarySell157$285.74$45K
2026-08-03
filed 2026-08-04
Reardon AndrewCLO & SecretarySell105$284.14$30K
2026-08-03
filed 2026-08-04
Reardon AndrewCLO & SecretarySell33$284.55$9K

Reported non-derivative purchases and sales (codes P/S) — which may be open-market or private; excludes option exercises, grants, and shares withheld for taxes. Dates shown are the trade date; a Form 4 can be filed days to years later. A sale can be routine (e.g. a pre-set 10b5-1 plan), so read individual transactions in context. From SEC Form 4. Not investment advice.

Short interest

Total shares sold short as of each twice-monthly FINRA settlement. Rising short interest means more investors are positioned against the stock; days to cover estimates how many trading days of average volume that position represents.

Shares short
2.4M
settled 2026-08-14
Change vs prior
+12.8%
vs previous settlement
Days to cover
8.76
at avg daily volume
Avg daily volume
279.4K
FINRA reported
SettlementShares shortChangeDays to cover
2026-08-142.4M+12.8%8.76
2026-07-312.2M+13.1%7.36
2026-07-151.9M-9.6%4.99
2026-06-302.1M+25.6%2.60
2026-06-151.7M+3.1%8.33
2026-05-291.6M+8.8%8.18
2026-05-151.5M+3.4%6.67
2026-04-301.5M+3.4%7.97

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data, which is included at no additional charge for your own personal or professional use; republishing or redistributing it is not permitted. Settlement dates are shown; FINRA publishes each settlement about nine business days later, so the latest figure can be two to four weeks old. Not presented as a percentage of float. No FINRA endorsement of this product is implied. Not investment advice.

Income statement (as reported)

 FY2025FY2024FY2023FY2022FY2021
Revenue$268.1M$167.1M$131.3M$196.2M$241.5M
Gross profit
Operating income$41.0M$-22.6M$11.9M$3.0M$103.9M
Net income$124.5M$-4.0M$52.2M$-33.4M$57.1M
Diluted EPS$6.13$-0.22$2.94$-1.98$3.31

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Balance sheet (as reported)

 FY2025FY2024FY2023FY2022FY2021
Cash and equivalents$174.9M$72.3M$23.0M$45.0M$19.5M
Current assets$832.3M$331.6M$237.4M$263.6M$464.8M
Total assets$1.56B$941.8M$787.2M$762.7M$1.30B
Current liabilities$37.4M$37.1M$16.8M$98.8M$41.7M
Long-term debt
Total liabilities$543.4M$111.3M$86.3M$165.2M$476.4M
Total equity$1.02B$830.4M$700.9M$597.5M$821.2M

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Cash flow (as reported)

 FY2025FY2024FY2023FY2022FY2021
Operating cash flow$49.4M$97.0M$49.6M$137.8M$78.8M
Capital expenditure$452,000$1.8M$3.5M$17.9M$8.8M
Free cash flow$48.9M$95.2M$46.1M$119.9M$70.0M

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Quarterly trend (as reported)

QuarterRevenueRevenue YoYNet incomeDiluted EPS
Q2 FY2026$63.7M33.7%$48.5M$2.22
Q1 FY2026$51.7M14.1%$-13.3M$-0.67
Q4 FY2025$59.7M39.4%$44.8M$2.17
Q3 FY2025$115.5M122.8%$117.3M$5.68
Q2 FY2025$47.6M14.7%$4.8M$0.24
Q1 FY2025$45.3M46.3%$-42.5M$-2.21
Q4 FY2024$42.8M52.4%$-31.1M$-1.78
Q3 FY2024$51.8M57.6%$-7.2M$-0.39

Latest 8 reported quarters, from company XBRL filings on SEC EDGAR.

Company facts

ExchangeNasdaq
SectorHealthcare
SIC industryPharmaceutical Preparations
Latest annual periodFY2025 (ended December 31, 2025)
Latest reported quarterQ2 FY2026 (ended June 30, 2026)
Oldest indexed filing2015
SEC CIK886163

Selected SEC filings

10-Q2026-08-07
View on EDGAR →
10-Q2026-05-08
View on EDGAR →
8-K2026-08-06
View on EDGAR →
8-K2026-07-14
View on EDGAR →
8-K2026-06-25
View on EDGAR →
8-K2026-06-22
View on EDGAR →

Largest pharmaceutical peers

All pharmaceutical stocksAll Healthcare companies →

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Data sourced from SEC EDGAR. Figures are as-reported and may be unaudited or restated; verify against the source filing before relying on them. Informational only. Not investment advice.