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Nasdaq · Healthcare

Janux Therapeutics, Inc. (JANX)

As-reported financials and SEC filings for Janux Therapeutics, Inc. The latest annual period is FY2025. The latest reported quarter is Q2 FY2026. Financial statements come straight from the company’s EDGAR filings; valuation figures such as P/E and market cap use market data.

About Janux Therapeutics, Inc.

Janux Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing novel immunotherapies for cancer and autoimmune diseases. It focuses on proprietary platforms called TRACTr, TRACIr, and ARM to create therapies that activate T cells to target tumors or autoreactive cells while aiming to reduce side effects. The company is conducting clinical trials for candidates targeting prostate cancer, multiple solid tumors, and autoimmune diseases.

Snapshot

Revenue
$10.0M
Revenue growth (YoY)
-5.6%
Net income
$-113.6M
Diluted EPS
$-1.83
Gross margin
Operating margin
Net margin
FCF margin
ROE
-11.9%
net income / fiscal-year-end equity
P/E
trailing when available, otherwise FY EPS
Market cap
$1.10B
Long-term debt / equity
non-current term debt only

Fundamentals are from SEC filings for FY2025, the latest annual period (ended December 31, 2025). P/E and market cap are derived from stored market prices, last retrieved on a rolling basis and typically within the past week.

What changed at Janux Therapeutics

  • Revenue fell 5.6% to $10M in FY2025, slower than the 31.0% the year before.
  • Operating margin is -1576.7% in FY2025, -671.3 pp against -905.4% in FY2021.
  • Free cash flow was negative $83M in FY2025.
  • Net loss widened to $114M in FY2025, from $69M in FY2024.

Computed from the as-reported figures in the statements below. A change we cannot state from filed figures is left out rather than estimated.

Peer comparison

Where Janux Therapeutics’s fundamentals sit among the 198 pharmaceutical companies. Each figure is ranked only against peers that report it, from lowest (left) to highest (right).

Revenue growth (YoY)-5.6%
25th percentile of 187
ROE-11.9%
58th percentile of 167
Short interest10.90d
81st percentile of 197

No reported insider transactions (codes P/S) in the last 90 days. For context, about 14% of companies in the universe saw any reported insider purchase (code P) in the same window. Browse insider activity →

Percentiles describe where a figure sits among industry peers reporting it (100th = highest). They are position within a peer group, not a rating, and not investment advice. Short interest ranking uses days to cover from FINRA Consolidated Short Interest data; FINRA is the owner and source of that data, included at no additional charge.

Institutional ownership

Held by 6 quant / multi-strat books among the superinvestors we track; no conviction manager currently reports a position.

Conviction investors
0
+6 quant / multi-strat
Initiated / added
6
1 new, 5 added
Reduced / exited
0
0 trimmed, 0 exited
Combined position
$93.9M
reported long value
InvestorAs ofPosition valueSharesChange
Point72 Asset ManagementquantQ2 2026$30.6M2.0MAdded
Two Sigma InvestmentsquantQ2 2026$18.5M1.2MAdded
Citadel AdvisorsquantQ2 2026$18.4M1.2MAdded
D. E. ShawquantQ2 2026$16.8M1.1MAdded
Millennium ManagementquantQ2 2026$7.7M504.5KAdded
AQR Capital ManagementquantQ2 2026$1.7M108.1KNew

From quarterly Form 13F filings, which can be up to 45 days delayed. Long US-listed positions only: excludes short positions, options, cash, bonds, and non-US holdings, so this is not a manager’s complete portfolio. Counts are of the investors we track, not all institutions. Not investment advice.

Recent insider activity

Non-derivative buys and sells (codes P/S) reported by officers, directors and 10% owners on SEC Form 4.

Buys (90d)
0
code P
Bought (90d)
code P value
Sells (90d)
0
Reported activity
Quiet
by $ value, 90d
Trade dateInsiderTypeSharesPriceValue
2026-06-02
filed 2026-06-04
Doyle Janeen NoelChief Corp. & Bus. Dev. OfcrSell4.1K$14.03$57K
2026-05-11
filed 2026-05-13
Dobek MariaVice President, AccountingSell2.0K$14.17$29K

Reported non-derivative purchases and sales (codes P/S) — which may be open-market or private; excludes option exercises, grants, and shares withheld for taxes. Dates shown are the trade date; a Form 4 can be filed days to years later. A sale can be routine (e.g. a pre-set 10b5-1 plan), so read individual transactions in context. From SEC Form 4. Not investment advice.

Short interest

Total shares sold short as of each twice-monthly FINRA settlement. Rising short interest means more investors are positioned against the stock; days to cover estimates how many trading days of average volume that position represents.

Shares short
6.6M
settled 2026-08-14
Change vs prior
+11.9%
vs previous settlement
Days to cover
10.90
at avg daily volume
Avg daily volume
607.9K
FINRA reported
SettlementShares shortChangeDays to cover
2026-08-146.6M+11.9%10.90
2026-07-315.9M-8.2%7.74
2026-07-156.5M-9.2%6.43
2026-06-307.1M-6.7%3.59
2026-06-157.6M-5.9%10.96
2026-05-298.1M+3.4%6.83
2026-05-157.8M-1.3%9.66
2026-04-307.9M+6.6%7.40

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data, which is included at no additional charge for your own personal or professional use; republishing or redistributing it is not permitted. Settlement dates are shown; FINRA publishes each settlement about nine business days later, so the latest figure can be two to four weeks old. Not presented as a percentage of float. No FINRA endorsement of this product is implied. Not investment advice.

Income statement (as reported)

 FY2025FY2024FY2023FY2022FY2021
Revenue$10.0M$10.6M$8.1M$8.6M$3.6M
Gross profit
Operating income$-157.7M$-98.8M$-73.0M$-67.1M$-32.9M
Net income$-113.6M$-69.0M$-58.3M$-63.1M$-32.7M
Diluted EPS$-1.83$-1.28$-1.32$-1.52$-1.39

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Balance sheet (as reported)

 FY2025FY2024FY2023FY2022FY2021
Cash and equivalents$52.3M$430.6M$19.2M$51.4M$35.6M
Current assets$975.9M$1.03B$349.2M$332.4M$377.0M
Total assets$1.00B$1.06B$380.4M$364.0M$379.8M
Current liabilities$25.0M$17.5M$13.0M$16.5M$12.8M
Long-term debt
Total liabilities$44.7M$38.7M$36.1M$43.3M$13.5M
Total equity$956.8M$1.02B$344.3M$320.7M$366.3M

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Cash flow (as reported)

 FY2025FY2024FY2023FY2022FY2021
Operating cash flow$-82.2M$-43.8M$-50.6M$-42.9M$-17.0M
Capital expenditure$1.0M$359,000$1.9M$6.4M$1.5M
Free cash flow$-83.3M$-44.2M$-52.4M$-49.4M$-18.5M

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Quarterly trend (as reported)

QuarterRevenueRevenue YoYNet incomeDiluted EPS
Q2 FY2026$10.3M$-22.0M$-0.35
Q1 FY2026$3.7M$-24.4M$-0.39
Q4 FY2025$0$-31.9M$-0.51
Q3 FY2025$10.0M2177.9%$-24.3M$-0.39
Q2 FY2025$0-100.0%$-33.9M$-0.55
Q1 FY2025$0-100.0%$-23.5M$-0.38
Q4 FY2024$0-100.0%$-20.2M$-0.36
Q3 FY2024$439,000-82.6%$-28.1M$-0.51

Latest 8 reported quarters, from company XBRL filings on SEC EDGAR.

Company facts

ExchangeNasdaq
SectorHealthcare
SIC industryPharmaceutical Preparations
Latest annual periodFY2025 (ended December 31, 2025)
Latest reported quarterQ2 FY2026 (ended June 30, 2026)
Oldest indexed filing2020
SEC CIK1817713

Selected SEC filings

10-K2026-02-26
View on EDGAR →
10-Q2026-08-06
View on EDGAR →
10-Q2026-05-07
View on EDGAR →
8-K2026-08-06
View on EDGAR →
8-K2026-06-23
View on EDGAR →
8-K2026-06-12
View on EDGAR →
8-K2026-05-07
View on EDGAR →

Largest pharmaceutical peers

All pharmaceutical stocksAll Healthcare companies →

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Data sourced from SEC EDGAR. Figures are as-reported and may be unaudited or restated; verify against the source filing before relying on them. Informational only. Not investment advice.