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Nasdaq · Healthcare

CYTOKINETICS INC (CYTK)

As-reported financials and SEC filings for CYTOKINETICS INC. The latest annual period is FY2025. The latest reported quarter is Q2 FY2026. Financial statements come straight from the company’s EDGAR filings; valuation figures such as P/E and market cap use market data.

About CYTOKINETICS INC

Cytokinetics Inc is a biopharmaceutical company that discovers, develops, and commercializes small molecule drugs targeting muscle function to treat diseases with impaired muscle performance. Its first approved product, MYQORZO (aficamten), is used to treat adults with symptomatic obstructive hypertrophic cardiomyopathy (oHCM) and is available in the United States, Europe, and China. The company focuses on cardiovascular and neuromuscular diseases and aims to expand its pipeline with additional muscle-directed investigational medicines.

Snapshot

Revenue
$88.0M
Revenue growth (YoY)
376.6%
Net income
$-785.0M
Diluted EPS
$-6.54
Gross margin
Operating margin
Net margin
FCF margin
ROE
net income / fiscal-year-end equity
P/E
trailing when available, otherwise FY EPS
Market cap
$11.01B
Long-term debt / equity
non-current term debt only

Fundamentals are from SEC filings for FY2025, the latest annual period (ended December 31, 2025). P/E and market cap are derived from stored market prices, last retrieved on a rolling basis and typically within the past week.

What changed at Cytokinetics

  • Revenue grew 376.6% to $88M in FY2025, faster than the 145.3% the year before.
  • Operating margin is -695.4% in FY2025, -430.9 pp against -264.5% in FY2021.
  • Most recent quarter Q2 FY2026: revenue $29M, down 57.1% from Q2 FY2025.
  • Free cash flow was negative $535M in FY2025.
  • Net loss widened to $785M in FY2025, from $590M in FY2024.

Computed from the as-reported figures in the statements below. A change we cannot state from filed figures is left out rather than estimated.

Peer comparison

Where Cytokinetics’s fundamentals sit among the 198 pharmaceutical companies. Each figure is ranked only against peers that report it, from lowest (left) to highest (right).

Revenue growth (YoY)+376.6%
92nd percentile of 187
Short interest7.69d
61st percentile of 197

Cytokinetics’s revenue growth of +376.6% ranks in the 92nd percentile of the 187 pharmaceutical companies reporting it.

No reported insider purchases (code P) in the last 90 days; 19 insider sales totaling $11.9M. For context, about 15% of companies in the universe saw any reported insider purchase (code P) in the same window. Browse insider activity →

Percentiles describe where a figure sits among industry peers reporting it (100th = highest). They are position within a peer group, not a rating, and not investment advice. Short interest ranking uses days to cover from FINRA Consolidated Short Interest data; FINRA is the owner and source of that data, included at no additional charge.

Institutional ownership

Held by 1 of the superinvestors we track (plus 6 quant / multi-strat books), based on each investor’s most recent 13F; periods vary by investor (newest: Q2 2026).

Conviction investors
1
+6 quant / multi-strat
Initiated / added
6
1 new, 5 added
Reduced / exited
1
1 trimmed, 0 exited
Combined position
$329.8M
reported long value
InvestorAs ofPosition valueSharesChange
Point72 Asset ManagementquantQ2 2026$135.3M1.6MAdded
D. E. ShawquantQ2 2026$89.3M1.0MAdded
Citadel AdvisorsquantQ2 2026$54.6M640.9KReduced
Two Sigma InvestmentsquantQ2 2026$27.0M317.4KAdded
AQR Capital ManagementquantQ2 2026$13.8M161.9KAdded
Millennium ManagementquantQ2 2026$9.3M109.7KAdded
Gotham Asset ManagementQ2 2026$457,2155.4KNew

From quarterly Form 13F filings, which can be up to 45 days delayed. Long US-listed positions only: excludes short positions, options, cash, bonds, and non-US holdings, so this is not a manager’s complete portfolio. Counts are of the investors we track, not all institutions. Not investment advice.

Recent insider activity

Non-derivative buys and sells (codes P/S) reported by officers, directors and 10% owners on SEC Form 4.

Buys (90d)
0
code P
Bought (90d)
code P value
Sells (90d)
19
$11.9M
Reported activity
Net selling
by $ value, 90d
Trade dateInsiderTypeSharesPriceValue
2026-09-01
PARSHALL B LYNNEDirectorSell5.0K$71.48$357K
2026-08-31
Callos AndrewEVP, Chief Commercial OfficerSell10.0K$70.24$702K
2026-08-31
Blum Robert IPresident & CEOSell7.5K$70.24$527K
2026-08-18
Malik Fady IbrahamEVP Research & DevelopmentSell3.5K$75.82$265K
2026-08-10
Blum Robert IPresident & CEOSell7.5K$76.76$576K
2026-07-30
Callos AndrewEVP, Chief Commercial OfficerSell14.0K$79.88$1.1M
2026-07-27
Blum Robert IPresident & CEOSell7.5K$80.87$607K
2026-07-21
filed 2026-07-23
Malik Fady IbrahamEVP Research & DevelopmentSell3.5K$80.59$282K
2026-07-13
filed 2026-07-14
Blum Robert IPresident & CEOSell7.5K$82.02$614K
2026-07-13
filed 2026-07-14
Blum Robert IPresident & CEOSell10$82.02$820
2026-07-07
Malik Fady IbrahamEVP Research & DevelopmentSell3.5K$86.62$303K
2026-07-01
filed 2026-07-02
Callos AndrewEVP, Chief Commercial OfficerSell15.0K$85.80$1.3M

Reported non-derivative purchases and sales (codes P/S) — which may be open-market or private; excludes option exercises, grants, and shares withheld for taxes. Dates shown are the trade date; a Form 4 can be filed days to years later. A sale can be routine (e.g. a pre-set 10b5-1 plan), so read individual transactions in context. From SEC Form 4. Not investment advice.

Short interest

Total shares sold short as of each twice-monthly FINRA settlement. Rising short interest means more investors are positioned against the stock; days to cover estimates how many trading days of average volume that position represents.

Shares short
16.3M
settled 2026-08-14
Change vs prior
+6.7%
vs previous settlement
Days to cover
7.69
at avg daily volume
Avg daily volume
2.1M
FINRA reported
SettlementShares shortChangeDays to cover
2026-08-1416.3M+6.7%7.69
2026-07-3115.3M-10.3%9.63
2026-07-1517.1M-3.0%8.99
2026-06-3017.6M+19.0%5.27
2026-06-1514.8M-4.7%9.30
2026-05-2915.5M-5.8%8.55
2026-05-1516.5M+3.6%3.38
2026-04-3015.9M+6.8%9.68

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data, which is included at no additional charge for your own personal or professional use; republishing or redistributing it is not permitted. Settlement dates are shown; FINRA publishes each settlement about nine business days later, so the latest figure can be two to four weeks old. Not presented as a percentage of float. No FINRA endorsement of this product is implied. Not investment advice.

Income statement (as reported)

 FY2025FY2024FY2023FY2022FY2021
Revenue$88.0M$18.5M$7.5M$94.6M$70.4M
Gross profit
Operating income$-612.3M$-536.2M$-496.2M$-324.2M$-186.3M
Net income$-785.0M$-589.5M$-526.2M$-389.0M$-215.3M
Diluted EPS$-6.54$-5.26$-5.45$-4.33$-2.80

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Balance sheet (as reported)

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Cash flow (as reported)

 FY2025FY2024FY2023FY2022FY2021
Operating cash flow$-510.0M$-395.9M$-414.3M$-299.5M$-142.5M
Capital expenditure$24.8M$3.9M$1.4M$11.3M$48.9M
Free cash flow$-534.8M$-399.8M$-415.7M$-310.9M$-191.4M

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Quarterly trend (as reported)

QuarterRevenueRevenue YoYNet incomeDiluted EPS
Q2 FY2026$28.6M-57.1%$-198.8M$-1.50
Q1 FY2026$19.4M1125.8%$-206.0M$-1.67
Q4 FY2025$17.8M$-183.0M
Q3 FY2025$1.9M318.1%$-306.2M$-2.55
Q2 FY2025$66.8M26714.9%$-134.4M$-1.12
Q1 FY2025$1.6M89.1%$-161.4M$-1.36
Q4 FY2024$-150.0M
Q3 FY2024$463,00022.5%$-160.5M$-1.36

Latest 8 reported quarters, from company XBRL filings on SEC EDGAR.

Company facts

ExchangeNasdaq
SectorHealthcare
SIC industryPharmaceutical Preparations
Latest annual periodFY2025 (ended December 31, 2025)
Latest reported quarterQ2 FY2026 (ended June 30, 2026)
Oldest indexed filing2021
SEC CIK1061983

Selected SEC filings

10-Q2026-08-06
View on EDGAR →
8-K2026-08-28
View on EDGAR →
8-K2026-08-13
View on EDGAR →
8-K2026-08-06
View on EDGAR →
8-K2026-05-27
View on EDGAR →

Largest pharmaceutical peers

All pharmaceutical stocksAll Healthcare companies →

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Data sourced from SEC EDGAR. Figures are as-reported and may be unaudited or restated; verify against the source filing before relying on them. Informational only. Not investment advice.