Revolution Medicines vs BIO-TECHNE (RVMD vs TECH)
Side by side from their SEC filings: revenue, margins, growth, returns and valuation, plus short interest, insider activity and institutional ownership.
BIO-TECHNE is the larger company by revenue ($1.2B vs $0). Revolution Medicines carries the larger market value ($39.6B vs $11.1B). BIO-TECHNE has grown revenue faster over the last 4 fiscal years (+31.0% cumulative vs -100.0%).
About Revolution Medicines
Revolution Medicines, Inc. is a clinical-stage precision oncology company that develops targeted therapies for cancers driven by RAS mutations. The company focuses on small molecule inhibitors called RAS(ON) Inhibitors, designed to target active forms of RAS proteins in various cancers, including pancreatic ductal adenocarcinoma, non-small cell lung cancer, and colorectal cancer. Its pipeline includes multiple oral inhibitors tailored to specific RAS mutations, and it conducts clinical trials to evaluate these therapies in cancer patients.
About BIO-TECHNE
Bio-Techne Corporation develops, manufactures, and sells life science reagents, instruments, and services for research, diagnostics, and bioprocessing markets worldwide. The company operates through two segments: Protein Sciences, which provides biological reagents and protein analysis tools for research and therapeutic development, and Diagnostics and Spatial Biology, which offers diagnostic assays, spatial biology solutions, and molecular diagnostic products. Bio-Techne serves customers including academic researchers, pharmaceutical and biotech companies, and clinical diagnostic laboratories.
Head to head (RVMD FY2025 vs TECH FY2025)
| Metric | RVMDFY2025 | TECHFY2025 |
|---|---|---|
| Revenue | $0 | $1.22B |
| Revenue growth (YoY) | — | 5.2% |
| Gross margin | — | 64.8% |
| Operating margin | — | 8.4% |
| Net margin | — | 6.0% |
| Net income | $-1.13B | $73.4M |
| Diluted EPS | $-5.95 | $0.46 |
| FCF margin | — | 21.0% |
| ROE | -69.3% | 3.8% |
| Debt / equity | — | 0.2× |
| Market cap | $39.58B | $11.11B |
| P/E (TTM) | — | 101.9× |
Fundamentals are from each company’s SEC filings (RVMD FY2025, TECH FY2025). P/E and market cap are derived from recent market prices and update daily.
Five-year trend (as reported)
Peer standing
Where each company ranks among the 71 biotech companies, on the same scale. Each figure is ranked only against peers that report it. Percentiles describe position in the distribution, not a rating.
| Metric | RVMD | TECH |
|---|---|---|
| ROE | -69.3%20th percentile of 61 | 3.8%73rd percentile of 61 |
| Short interest (days to cover) | 2.99d24th percentile of 71 | 1.47d10th percentile of 71 |
Short interest
| FINRA settlement data | RVMD | TECH |
|---|---|---|
| Shares sold short | 12.9M | 15.9M |
| Change vs prior settlement | +4.9% | -12.6% |
| Days to cover | 2.99 | 1.47 |
| As of settlement | 2026-06-30 | 2026-06-30 |
Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data; republishing or redistributing it is not permitted. Not presented as a percentage of float. No FINRA endorsement of this product is implied.
Insider activity (last 90 days)
| Form 4 open-market activity | RVMD | TECH |
|---|---|---|
| Buys | 0 | 0 |
| Sells | 33 ($24.9M) | 1 ($320,386) |
Open-market purchases and sales reported on SEC Form 4 (grants, exercises and tax withholding excluded). For context, about 16% of covered companies saw any open-market insider buy in a 90-day window.
Held by the same investors
4 tracked 13F managers hold both Revolution Medicines and BIO-TECHNE as of their latest quarterly filings: AQR Capital Management, Citadel Advisors, Gotham Asset Management, Two Sigma Investments. See which superinvestors hold your own portfolio with the smart money checker.
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Data sourced from SEC EDGAR (public domain). Figures are as-reported and may be unaudited or restated; verify against the source filings before relying on them. Comparisons are descriptive (higher or lower on a reported figure), not a rating or a recommendation. Informational only. Not investment advice.