Biogen vs Revolution Medicines (BIIB vs RVMD)
Side by side from their SEC filings: revenue, margins, growth, returns and valuation, plus short interest, insider activity and institutional ownership.
Biogen is the larger company by revenue ($9.9B vs $0). Revolution Medicines carries the larger market value ($39.6B vs $30.9B). Biogen has grown revenue faster over the last 4 fiscal years (-9.9% cumulative vs -100.0%).
About Biogen
Biogen Inc. is a global biopharmaceutical company that discovers, develops, and delivers therapies for serious and complex diseases. It markets treatments for multiple sclerosis, spinal muscular atrophy, Friedreich's ataxia, amyotrophic lateral sclerosis, and collaborates on therapies for Alzheimer's disease and other conditions. The company also develops biosimilars and engages in research collaborations and acquisitions to advance its pipeline in neurology, immunology, and rare diseases.
About Revolution Medicines
Revolution Medicines, Inc. is a clinical-stage precision oncology company that develops targeted therapies for cancers driven by RAS mutations. The company focuses on small molecule inhibitors called RAS(ON) Inhibitors, designed to target active forms of RAS proteins in various cancers, including pancreatic ductal adenocarcinoma, non-small cell lung cancer, and colorectal cancer. Its pipeline includes multiple oral inhibitors tailored to specific RAS mutations, and it conducts clinical trials to evaluate these therapies in cancer patients.
Head to head (BIIB FY2025 vs RVMD FY2025)
| Metric | BIIBFY2025 | RVMDFY2025 |
|---|---|---|
| Revenue | $9.89B | $0 |
| Revenue growth (YoY) | 2.2% | — |
| Gross margin | 75.7% | — |
| Operating margin | — | — |
| Net margin | 13.1% | — |
| Net income | $1.29B | $-1.13B |
| Diluted EPS | $8.79 | $-5.95 |
| FCF margin | 20.7% | — |
| ROE | 7.1% | -69.3% |
| Debt / equity | 0.3× | — |
| Market cap | $30.86B | $39.58B |
| P/E (TTM) | 22.5× | — |
Fundamentals are from each company’s SEC filings (BIIB FY2025, RVMD FY2025). P/E and market cap are derived from recent market prices and update daily.
Five-year trend (as reported)
Peer standing
Where each company ranks among the 71 biotech companies, on the same scale. Each figure is ranked only against peers that report it. Percentiles describe position in the distribution, not a rating.
| Metric | BIIB | RVMD |
|---|---|---|
| ROE | 7.1%77th percentile of 61 | -69.3%20th percentile of 61 |
| Short interest (days to cover) | 4.14d43rd percentile of 71 | 2.99d24th percentile of 71 |
Short interest
| FINRA settlement data | BIIB | RVMD |
|---|---|---|
| Shares sold short | 5.7M | 12.9M |
| Change vs prior settlement | +10.3% | +4.9% |
| Days to cover | 4.14 | 2.99 |
| As of settlement | 2026-06-30 | 2026-06-30 |
Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data; republishing or redistributing it is not permitted. Not presented as a percentage of float. No FINRA endorsement of this product is implied.
Insider activity (last 90 days)
| Form 4 open-market activity | BIIB | RVMD |
|---|---|---|
| Buys | — | 0 |
| Sells | — | 33 ($24.9M) |
Open-market purchases and sales reported on SEC Form 4 (grants, exercises and tax withholding excluded). For context, about 16% of covered companies saw any open-market insider buy in a 90-day window.
Held by the same investors
6 tracked 13F managers hold both Biogen and Revolution Medicines as of their latest quarterly filings: AQR Capital Management, Citadel Advisors, Gotham Asset Management, Millennium Management, Renaissance Technologies, Two Sigma Investments. See which superinvestors hold your own portfolio with the smart money checker.
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Data sourced from SEC EDGAR (public domain). Figures are as-reported and may be unaudited or restated; verify against the source filings before relying on them. Comparisons are descriptive (higher or lower on a reported figure), not a rating or a recommendation. Informational only. Not investment advice.