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Nasdaq · Healthcare

TScan Therapeutics, Inc. (TCRX)

As-reported financials and SEC filings for TScan Therapeutics, Inc. The latest annual period is FY2025. The latest reported quarter is Q2 FY2026. Financial statements come straight from the company’s EDGAR filings; valuation figures such as P/E and market cap use market data.

About TScan Therapeutics, Inc.

TScan Therapeutics, Inc. is a clinical-stage biotechnology company that develops T cell receptor-engineered T cell therapies for cancer treatment. Its lead product candidate, TSC-101, targets acute myeloid leukemia and myelodysplastic syndrome in patients undergoing allogeneic hematopoietic cell transplantation. The company also develops multiplex TCR-T therapies for solid tumors and explores treatments for T cell-driven autoimmune disorders.

Snapshot

Revenue
$10.3M
Revenue growth (YoY)
266.7%
Net income
$-129.8M
Diluted EPS
$-1.00
Gross margin
Operating margin
Net margin
FCF margin
ROE
-105.4%
net income / fiscal-year-end equity
P/E
trailing when available, otherwise FY EPS
Market cap
$45.2M
Long-term debt / equity
0.26×
non-current term debt only

Fundamentals are from SEC filings for FY2025, the latest annual period (ended December 31, 2025). P/E and market cap are derived from stored market prices, last retrieved on a rolling basis and typically within the past week.

What changed at TScan Therapeutics

  • Revenue grew 266.7% to $10M in FY2025, after a 86.6% decline the year before.
  • Operating margin is -1315.4% in FY2025, -835.7 pp against -479.6% in FY2021.
  • Most recent quarter Q2 FY2026: revenue $1M, down 65.8% from Q2 FY2025.
  • Free cash flow was negative $140M in FY2025.
  • Net loss widened to $130M in FY2025, from $127M in FY2024.

Computed from the as-reported figures in the statements below. A change we cannot state from filed figures is left out rather than estimated.

Peer comparison

Where TScan Therapeutics’s fundamentals sit among the 71 biotech companies. Each figure is ranked only against peers that report it, from lowest (left) to highest (right).

Revenue growth (YoY)+266.7%
90th percentile of 64
ROE-105.4%
15th percentile of 61
Long-term debt / equity0.26×
47th percentile of 20
Short interest4.24d
24th percentile of 71

TScan Therapeutics’s revenue growth of +266.7% ranks in the 90th percentile of the 64 biotech companies reporting it. TScan Therapeutics’s return on equity of -105.4% ranks in the 15th percentile of the 61 biotech companies reporting it.

No reported insider transactions (codes P/S) in the last 90 days. For context, about 15% of companies in the universe saw any reported insider purchase (code P) in the same window. Browse insider activity →

Percentiles describe where a figure sits among industry peers reporting it (100th = highest). They are position within a peer group, not a rating, and not investment advice. Short interest ranking uses days to cover from FINRA Consolidated Short Interest data; FINRA is the owner and source of that data, included at no additional charge.

Institutional ownership

Held by 5 quant / multi-strat books among the superinvestors we track; no conviction manager currently reports a position.

Conviction investors
0
+5 quant / multi-strat
Initiated / added
3
0 new, 3 added
Reduced / exited
2
2 trimmed, 0 exited
Combined position
$5.9M
reported long value
InvestorAs ofPosition valueSharesChange
Two Sigma InvestmentsquantQ2 2026$1.9M1.9MAdded
Renaissance TechnologiesquantQ2 2026$1.3M1.3MReduced
Millennium ManagementquantQ2 2026$1.1M1.2MReduced
Citadel AdvisorsquantQ2 2026$989,0261.0MAdded
D. E. ShawquantQ2 2026$537,489548.4KAdded

From quarterly Form 13F filings, which can be up to 45 days delayed. Long US-listed positions only: excludes short positions, options, cash, bonds, and non-US holdings, so this is not a manager’s complete portfolio. Counts are of the investors we track, not all institutions. Not investment advice.

Short interest

Total shares sold short as of each twice-monthly FINRA settlement. Rising short interest means more investors are positioned against the stock; days to cover estimates how many trading days of average volume that position represents.

Shares short
1.6M
settled 2026-08-14
Change vs prior
+2.7%
vs previous settlement
Days to cover
4.24
at avg daily volume
Avg daily volume
377.9K
FINRA reported
SettlementShares shortChangeDays to cover
2026-08-141.6M+2.7%4.24
2026-07-311.6M+12.6%2.78
2026-07-151.4M+95.5%1.19
2026-06-30708.2K-7.1%1.00
2026-06-15762.5K-18.4%1.94
2026-05-29934.3K+6.6%2.04
2026-05-15876.6K+0.7%1.04
2026-04-30870.2K-7.7%1.00

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data, which is included at no additional charge for your own personal or professional use; republishing or redistributing it is not permitted. Settlement dates are shown; FINRA publishes each settlement about nine business days later, so the latest figure can be two to four weeks old. Not presented as a percentage of float. No FINRA endorsement of this product is implied. Not investment advice.

Income statement (as reported)

 FY2025FY2024FY2023FY2022FY2021
Revenue$10.3M$2.8M$21.0M$13.5M$10.1M
Gross profit
Operating income$-135.8M$-134.8M$-93.5M$-66.6M$-48.6M
Net income$-129.8M$-127.5M$-89.2M$-66.2M$-48.6M
Diluted EPS$-1.00$-1.14$-1.36$-2.75$-2.08

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Balance sheet (as reported)

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Cash flow (as reported)

 FY2025FY2024FY2023FY2022FY2021
Operating cash flow$-135.3M$-110.8M$-61.4M$-66.5M$-48.7M
Capital expenditure$4.4M$3.8M$3.1M$4.2M$9.9M
Free cash flow$-139.7M$-114.6M$-64.5M$-70.7M$-58.6M

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Quarterly trend (as reported)

QuarterRevenueRevenue YoYNet incomeDiluted EPS
Q2 FY2026$1.1M-65.8%$-30.4M$-0.23
Q1 FY2026$982,000-54.8%$-28.7M$-0.22
Q4 FY2025$2.6M286.0%$-23.0M$-0.18
Q3 FY2025$2.5M139.4%$-35.7M$-0.28
Q2 FY2025$3.1M473.9%$-37.0M$-0.28
Q1 FY2025$2.2M283.6%$-34.1M$-0.26
Q4 FY2024$665,000-90.8%$-35.8M$-0.30
Q3 FY2024$1.0M-73.0%$-29.9M$-0.25

Latest 8 reported quarters, from company XBRL filings on SEC EDGAR.

Company facts

ExchangeNasdaq
SectorHealthcare
SIC industryBiological Products, (No Diagnostic Substances)
Latest annual periodFY2025 (ended December 31, 2025)
Latest reported quarterQ2 FY2026 (ended June 30, 2026)
Oldest indexed filing2019
SEC CIK1783328

Selected SEC filings

10-K2026-03-04
View on EDGAR →
10-Q2026-08-12
View on EDGAR →
10-Q2026-05-06
View on EDGAR →
10-Q2025-11-12
View on EDGAR →
10-Q2025-08-12
View on EDGAR →
8-K2026-08-18
View on EDGAR →
8-K2026-08-12
View on EDGAR →
8-K2026-06-22
View on EDGAR →

Largest biotech peers

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Data sourced from SEC EDGAR. Figures are as-reported and may be unaudited or restated; verify against the source filing before relying on them. Informational only. Not investment advice.