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Nasdaq · Healthcare

Sarepta Therapeutics, Inc. (SRPT)

As-reported financials and SEC filings for Sarepta Therapeutics, Inc. The latest annual period is FY2025. The latest reported quarter is Q2 FY2026. Financial statements come straight from the company’s EDGAR filings; valuation figures such as P/E and market cap use market data.

About Sarepta Therapeutics, Inc.

Sarepta Therapeutics, Inc. is a biopharmaceutical company that develops RNA-targeted therapeutics, siRNA knockdown therapies, and gene therapies for rare diseases. The company has commercialized four approved products for treating Duchenne muscular dystrophy and is developing additional therapies for neuromuscular disorders such as Facioscapulohumeral muscular dystrophy and Limb-Girdle muscular dystrophy. Sarepta serves patients with rare genetic diseases by applying proprietary technologies and collaborating with strategic partners.

Snapshot

Revenue
$2.20B
Revenue growth (YoY)
15.6%
Net income
$-713.4M
Diluted EPS
$-7.13
Gross margin
Operating margin
-31.8%
Net margin
-32.5%
FCF margin
-14.0%
ROE
-62.5%
net income / fiscal-year-end equity
P/E
trailing when available, otherwise FY EPS
Market cap
$2.20B
Long-term debt / equity
0.73×
non-current term debt only

Fundamentals are from SEC filings for FY2025, the latest annual period (ended December 31, 2025). P/E and market cap are derived from stored market prices, last retrieved on a rolling basis and typically within the past week.

What changed at Sarepta Therapeutics

  • Revenue grew 15.6% to $2.2B in FY2025, slower than the 66.1% the year before.
  • Operating margin is -31.8% in FY2025, +43.2 pp against -75.1% in FY2021.
  • Most recent quarter Q2 FY2026: revenue $329M, down 35.9% from Q2 FY2025.
  • Free cash flow was negative $307M in FY2025.
  • Net income turned to a $713M loss in FY2025, from a $235M profit in FY2024.

Computed from the as-reported figures in the statements below. A change we cannot state from filed figures is left out rather than estimated.

Peer comparison

Where Sarepta Therapeutics’s fundamentals sit among the 198 pharmaceutical companies. Each figure is ranked only against peers that report it, from lowest (left) to highest (right).

Operating margin-31.8%
21st percentile of 113
Net margin-32.5%
19th percentile of 122
FCF margin-14.0%
28th percentile of 110
Revenue growth (YoY)+15.6%
57th percentile of 187
ROE-62.5%
28th percentile of 167
Long-term debt / equity0.73×
62nd percentile of 64
Short interest9.07d
68th percentile of 197

No reported insider transactions (codes P/S) in the last 90 days. For context, about 15% of companies in the universe saw any reported insider purchase (code P) in the same window. Browse insider activity →

Percentiles describe where a figure sits among industry peers reporting it (100th = highest). They are position within a peer group, not a rating, and not investment advice. Short interest ranking uses days to cover from FINRA Consolidated Short Interest data; FINRA is the owner and source of that data, included at no additional charge.

Institutional ownership

Held by 1 of the superinvestors we track (plus 5 quant / multi-strat books), based on each investor’s most recent 13F; periods vary by investor (newest: Q2 2026).

Conviction investors
1
+5 quant / multi-strat
Initiated / added
3
1 new, 2 added
Reduced / exited
6
3 trimmed, 3 exited
Combined position
$213.0M
reported long value
InvestorAs ofPosition valueSharesChange
Two Sigma InvestmentsquantQ2 2026$82.6M4.6MAdded
AQR Capital ManagementquantQ2 2026$76.9M4.3MReduced
Millennium ManagementquantQ2 2026$21.4M1.2MReduced
Renaissance TechnologiesquantQ2 2026$20.2M1.1MReduced
Point72 Asset ManagementquantQ2 2026$9.2M510.9KNew
Bridgewater AssociatesQ2 2026$2.7M152.1KAdded

No longer held by: Citadel Advisors (as of Q2 2026), D. E. Shaw (as of Q2 2026), Gotham Asset Management (as of Q2 2026)

From quarterly Form 13F filings, which can be up to 45 days delayed. Long US-listed positions only: excludes short positions, options, cash, bonds, and non-US holdings, so this is not a manager’s complete portfolio. Counts are of the investors we track, not all institutions. Not investment advice.

Short interest

Total shares sold short as of each twice-monthly FINRA settlement. Rising short interest means more investors are positioned against the stock; days to cover estimates how many trading days of average volume that position represents.

Shares short
27.0M
settled 2026-08-14
Change vs prior
-1.9%
vs previous settlement
Days to cover
9.07
at avg daily volume
Avg daily volume
3.0M
FINRA reported
SettlementShares shortChangeDays to cover
2026-08-1427.0M-1.9%9.07
2026-07-3127.6M-3.2%8.77
2026-07-1528.5M-0.9%9.22
2026-06-3028.7M+14.2%5.75
2026-06-1525.2M+0.1%9.10
2026-05-2925.1M+0.4%9.44
2026-05-1525.0M+0.4%7.32
2026-04-3024.9M-1.6%9.54

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data, which is included at no additional charge for your own personal or professional use; republishing or redistributing it is not permitted. Settlement dates are shown; FINRA publishes each settlement about nine business days later, so the latest figure can be two to four weeks old. Not presented as a percentage of float. No FINRA endorsement of this product is implied. Not investment advice.

Income statement (as reported)

 FY2025FY2024FY2023FY2022FY2021
Revenue$2.20B$1.90B$1.14B$843.8M$612.4M
Gross profit
Operating income$-699.8M$218.1M$-267.8M$-536.2M$-459.7M
Net income$-713.4M$235.2M$-536.0M$-703.5M$-418.8M
Diluted EPS$-7.13$2.34$-5.80$-8.03$-5.15

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Balance sheet (as reported)

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Cash flow (as reported)

 FY2025FY2024FY2023FY2022FY2021
Operating cash flow$-205.5M$-205.8M$-501.0M$-325.3M$-443.2M
Capital expenditure$102.0M$137.0M$76.1M$30.8M$38.5M
Free cash flow$-307.5M$-342.7M$-577.1M$-356.2M$-481.7M

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Quarterly trend (as reported)

QuarterRevenueRevenue YoYNet incomeDiluted EPS
Q2 FY2026$328.7M-35.9%$-4.9M$-0.05
Q1 FY2026$730.8M19.5%$331.0M$2.88
Q4 FY2025$369.6M-42.1%$-282.8M$-2.70
Q3 FY2025$370.0M-13.9%$-50.6M$-0.50
Q2 FY2025$513.1M42.3%$196.9M$1.89
Q1 FY2025$611.5M70.1%$-447.5M$-4.60
Q4 FY2024$638.2M74.8%$159.0M$1.20
Q3 FY2024$429.8M38.9%$33.6M$0.34

Latest 8 reported quarters, from company XBRL filings on SEC EDGAR.

Company facts

ExchangeNasdaq
SectorHealthcare
SIC industryPharmaceutical Preparations
Latest annual periodFY2025 (ended December 31, 2025)
Latest reported quarterQ2 FY2026 (ended June 30, 2026)
Oldest indexed filing2011
SEC CIK873303

Selected SEC filings

10-K2026-03-02
View on EDGAR →
10-Q2026-08-05
View on EDGAR →
10-Q2026-05-06
View on EDGAR →
8-K2026-08-05
View on EDGAR →
8-K2026-07-27
View on EDGAR →
8-K2026-06-04
View on EDGAR →
8-K2026-05-06
View on EDGAR →

Largest pharmaceutical peers

All pharmaceutical stocksAll Healthcare companies →

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Data sourced from SEC EDGAR. Figures are as-reported and may be unaudited or restated; verify against the source filing before relying on them. Informational only. Not investment advice.