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Nasdaq · Healthcare

REGENXBIO Inc. (RGNX)

As-reported financials and SEC filings for REGENXBIO Inc. The latest annual period is FY2025. The latest reported quarter is Q2 FY2026. Financial statements come straight from the company’s EDGAR filings; valuation figures such as P/E and market cap use market data.

About REGENXBIO Inc.

REGENXBIO Inc. is a clinical-stage biotechnology company that develops gene therapies using its proprietary NAV Technology Platform, which includes a large portfolio of adeno-associated virus (AAV) vectors. The company focuses on creating one-time treatments for diseases such as retinal, neuromuscular, and neurodegenerative disorders. REGENXBIO also sublicenses its NAV vectors to other biopharmaceutical companies and operates its own manufacturing facility to produce AAV therapeutics.

Snapshot

Revenue
$170.4M
Revenue growth (YoY)
104.5%
Net income
$-193.9M
Diluted EPS
$-3.76
Gross margin
Operating margin
Net margin
FCF margin
ROE
-188.7%
net income / fiscal-year-end equity
P/E
trailing when available, otherwise FY EPS
Market cap
$637.7M
Long-term debt / equity
non-current term debt only

Fundamentals are from SEC filings for FY2025, the latest annual period (ended December 31, 2025). P/E and market cap are derived from stored market prices, last retrieved on a rolling basis and typically within the past week.

What changed at REGENXBIO

  • Revenue grew 104.5% to $170M in FY2025, after a 7.7% decline the year before.
  • Operating margin is now a 94.6% loss in FY2025, from 34.0% in FY2021.
  • Most recent quarter Q2 FY2026: revenue $108M, up 405.7% from Q2 FY2025.
  • Free cash flow was negative $126M in FY2025.
  • Net loss narrowed to $194M in FY2025, from $227M in FY2024.

Computed from the as-reported figures in the statements below. A change we cannot state from filed figures is left out rather than estimated.

Peer comparison

Where REGENXBIO’s fundamentals sit among the 71 biotech companies. Each figure is ranked only against peers that report it, from lowest (left) to highest (right).

Revenue growth (YoY)+104.5%
79th percentile of 64
ROE-188.7%
5th percentile of 61
Short interest7.77d
47th percentile of 71

REGENXBIO’s return on equity of -188.7% ranks in the 5th percentile of the 61 biotech companies reporting it.

2 reported insider purchases (code P) totaling $949,382 in the last 90 days, against 3 sales totaling $718,232. For context, about 15% of companies in the universe saw any reported insider purchase (code P) in the same window. Browse insider activity →

Percentiles describe where a figure sits among industry peers reporting it (100th = highest). They are position within a peer group, not a rating, and not investment advice. Short interest ranking uses days to cover from FINRA Consolidated Short Interest data; FINRA is the owner and source of that data, included at no additional charge.

Institutional ownership

Held by 6 quant / multi-strat books among the superinvestors we track; no conviction manager currently reports a position.

Conviction investors
0
+6 quant / multi-strat
Initiated / added
5
1 new, 4 added
Reduced / exited
2
1 trimmed, 1 exited
Combined position
$49.9M
reported long value
InvestorAs ofPosition valueSharesChange
AQR Capital ManagementquantQ2 2026$16.5M1.4MAdded
D. E. ShawquantQ2 2026$8.5M712.8KAdded
Two Sigma InvestmentsquantQ2 2026$8.0M669.8KAdded
Citadel AdvisorsquantQ2 2026$8.0M669.0KNew
Millennium ManagementquantQ2 2026$5.8M480.8KAdded
Renaissance TechnologiesquantQ2 2026$3.1M256.7KReduced

No longer held by: Point72 Asset Management (as of Q2 2026)

From quarterly Form 13F filings, which can be up to 45 days delayed. Long US-listed positions only: excludes short positions, options, cash, bonds, and non-US holdings, so this is not a manager’s complete portfolio. Counts are of the investors we track, not all institutions. Not investment advice.

Recent insider activity

Non-derivative buys and sells (codes P/S) reported by officers, directors and 10% owners on SEC Form 4.

Buys (90d)
2
1 insider
Bought (90d)
$949K
code P value
Sells (90d)
3
$718K
Reported activity
Net buying
by $ value, 90d
Trade dateInsiderTypeSharesPriceValue
2026-08-27
Ciongoli Gregory AustinDirectorBuy53.4K$9.36$500K
2026-08-26
filed 2026-08-27
Ciongoli Gregory AustinDirectorBuy49.2K$9.14$450K
2026-07-02
filed 2026-07-06
PAKOLA STEVEChief Medical OfficerSell2.2K$13.64$29K
2026-07-01
PAKOLA STEVEChief Medical OfficerSell36.7K$12.86$472K
2026-06-29
filed 2026-07-01
PAKOLA STEVEChief Medical OfficerSell19.6K$11.04$216K
2026-05-11
filed 2026-05-13
PAKOLA STEVEChief Medical OfficerSell15.3K$11.02$169K

Reported non-derivative purchases and sales (codes P/S) — which may be open-market or private; excludes option exercises, grants, and shares withheld for taxes. Dates shown are the trade date; a Form 4 can be filed days to years later. A sale can be routine (e.g. a pre-set 10b5-1 plan), so read individual transactions in context. From SEC Form 4. Not investment advice.

Short interest

Total shares sold short as of each twice-monthly FINRA settlement. Rising short interest means more investors are positioned against the stock; days to cover estimates how many trading days of average volume that position represents.

Shares short
8.2M
settled 2026-08-14
Change vs prior
+13.9%
vs previous settlement
Days to cover
7.77
at avg daily volume
Avg daily volume
1.1M
FINRA reported
SettlementShares shortChangeDays to cover
2026-08-148.2M+13.9%7.77
2026-07-317.2M-16.6%3.79
2026-07-158.6M-17.5%3.29
2026-06-3010.5M+12.9%3.19
2026-06-159.3M+11.8%6.96
2026-05-298.3M+16.1%4.50
2026-05-157.1M+6.6%3.19
2026-04-306.7M-3.6%12.13

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data, which is included at no additional charge for your own personal or professional use; republishing or redistributing it is not permitted. Settlement dates are shown; FINRA publishes each settlement about nine business days later, so the latest figure can be two to four weeks old. Not presented as a percentage of float. No FINRA endorsement of this product is implied. Not investment advice.

Income statement (as reported)

 FY2025FY2024FY2023FY2022FY2021
Revenue$170.4M$83.3M$90.2M$112.7M$470.3M
Gross profit$49.8M$53.0M$58.2M$418.5M
Operating income$-161.2M$-233.3M$-268.1M$-262.9M$160.0M
Net income$-193.9M$-227.1M$-263.5M$-280.3M$127.8M
Diluted EPS$-3.76$-4.59$-6.02$-6.50$2.91

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Balance sheet (as reported)

 FY2025FY2024FY2023FY2022FY2021
Cash and equivalents$34.5M$57.5M$34.5M$97.0M$345.2M
Current assets$281.3M$278.0M$335.0M$416.0M$518.8M
Total assets$453.0M$466.0M$574.0M$833.3M$1.11B
Current liabilities$118.1M$103.2M$130.3M$130.4M$130.5M
Long-term debt
Total liabilities$350.3M$206.3M$262.2M$317.1M$349.6M
Total equity$102.7M$259.7M$311.7M$516.2M$764.3M

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Cash flow (as reported)

 FY2025FY2024FY2023FY2022FY2021
Operating cash flow$-124.0M$-173.1M$-218.4M$-207.5M$218.9M
Capital expenditure$2.4M$2.4M$10.0M$30.7M$84.2M
Free cash flow$-126.4M$-175.6M$-228.4M$-238.2M$134.7M

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Quarterly trend (as reported)

QuarterRevenueRevenue YoYNet incomeDiluted EPS
Q2 FY2026$108.0M405.7%$22.7M$0.43
Q1 FY2026$6.4M-92.8%$-90.1M$-1.72
Q4 FY2025$30.3M43.0%$-67.1M$-1.30
Q3 FY2025$29.7M22.9%$-61.9M$-1.20
Q2 FY2025$21.4M-4.2%$-70.9M$-1.38
Q1 FY2025$89.0M469.8%$6.1M$0.12
Q4 FY2024$21.2M-4.5%$-51.2M$-1.01
Q3 FY2024$24.2M-16.3%$-59.6M$-1.17

Latest 8 reported quarters, from company XBRL filings on SEC EDGAR.

Company facts

ExchangeNasdaq
SectorHealthcare
SIC industryBiological Products, (No Diagnostic Substances)
Latest annual periodFY2025 (ended December 31, 2025)
Latest reported quarterQ2 FY2026 (ended June 30, 2026)
Oldest indexed filing2013
SEC CIK1590877

Selected SEC filings

10-K2026-03-05
View on EDGAR →
10-Q2026-08-06
View on EDGAR →
10-Q2026-05-14
View on EDGAR →
8-K2026-08-25
View on EDGAR →
8-K2026-08-24
View on EDGAR →
8-K2026-08-06
View on EDGAR →
8-K2026-07-20
View on EDGAR →

Largest biotech peers

All biotech stocksAll Healthcare companies →

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Data sourced from SEC EDGAR. Figures are as-reported and may be unaudited or restated; verify against the source filing before relying on them. Informational only. Not investment advice.