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Nasdaq · Healthcare

BeOne Medicines Ltd. (ONC)

As-reported financials and SEC filings for BeOne Medicines Ltd. The latest annual period is FY2025. The latest reported quarter is Q2 FY2026. Financial statements come straight from the company’s EDGAR filings; valuation figures such as P/E and market cap use market data.

About BeOne Medicines Ltd.

BeOne Medicines Ltd. is a global oncology company that discovers and develops cancer treatments, focusing on hematology and solid tumors. Its main products include BRUKINSA, a Bruton’s tyrosine kinase inhibitor for B-cell malignancies, sonrotoclax, a BCL2 inhibitor for chronic lymphocytic leukemia and mantle cell lymphoma, and TEVIMBRA, an anti-PD-1 monoclonal antibody for solid tumors. The company serves cancer patients worldwide and operates clinical development and manufacturing facilities across multiple continents.

Snapshot

Revenue
$5.34B
Revenue growth (YoY)
40.2%
Net income
$286.9M
Diluted EPS
$0.19
Gross margin
Operating margin
8.4%
Net margin
5.4%
FCF margin
17.6%
ROE
6.6%
net income / fiscal-year-end equity
P/E
64.4×
trailing when available, otherwise FY EPS
Market cap
$40.57B
Long-term debt / equity
0.22×
non-current term debt only

Fundamentals are from SEC filings for FY2025, the latest annual period (ended December 31, 2025). P/E and market cap are derived from stored market prices, last retrieved on a rolling basis and typically within the past week.

What changed at BeOne Medicines

  • Revenue grew 40.2% to $5.3B in FY2025, slower than the 55.0% the year before.
  • Operating margin turned positive at 8.4% in FY2025, from a 122.3% operating loss in FY2021.
  • Most recent quarter Q2 FY2026: revenue $1.7B, up 29.6% from Q2 FY2025.
  • Free cash flow was $942M in FY2025, 17.6% of revenue.
  • Net income turned positive at $287M in FY2025, from a $645M loss in FY2024.

Computed from the as-reported figures in the statements below. A change we cannot state from filed figures is left out rather than estimated.

Peer comparison

Where BeOne Medicines’s fundamentals sit among the 198 pharmaceutical companies. Each figure is ranked only against peers that report it, from lowest (left) to highest (right).

Operating margin8.4%
60th percentile of 113
Net margin5.4%
60th percentile of 122
FCF margin17.6%
72nd percentile of 110
Revenue growth (YoY)+40.2%
70th percentile of 187
ROE6.6%
72nd percentile of 167
P/E64.4×
83rd percentile of 60
Long-term debt / equity0.22×
35th percentile of 64
Short interest2.80d
22nd percentile of 197

No reported insider purchases (code P) in the last 90 days; 122 insider sales totaling $302.9M. For context, about 15% of companies in the universe saw any reported insider purchase (code P) in the same window. Browse insider activity →

Percentiles describe where a figure sits among industry peers reporting it (100th = highest). They are position within a peer group, not a rating, and not investment advice. Short interest ranking uses days to cover from FINRA Consolidated Short Interest data; FINRA is the owner and source of that data, included at no additional charge.

Institutional ownership

Held by 4 quant / multi-strat books among the superinvestors we track; no conviction manager currently reports a position.

Conviction investors
0
+4 quant / multi-strat
Initiated / added
4
0 new, 4 added
Reduced / exited
0
0 trimmed, 0 exited
Combined position
$671.8M
reported long value
InvestorAs ofPosition valueSharesChange
Citadel AdvisorsquantQ2 2026$406.2M1.4MAdded
Millennium ManagementquantQ2 2026$154.8M543.3KAdded
Two Sigma InvestmentsquantQ2 2026$81.7M286.6KAdded
Renaissance TechnologiesquantQ2 2026$29.1M102.0KAdded

From quarterly Form 13F filings, which can be up to 45 days delayed. Long US-listed positions only: excludes short positions, options, cash, bonds, and non-US holdings, so this is not a manager’s complete portfolio. Counts are of the investors we track, not all institutions. Not investment advice.

Recent insider activity

Non-derivative buys and sells (codes P/S) reported by officers, directors and 10% owners on SEC Form 4.

Buys (90d)
0
code P
Bought (90d)
code P value
Sells (90d)
122
$302.9M
Reported activity
Net selling
by $ value, 90d
Trade dateInsiderTypeSharesPriceValue
2026-08-25
filed 2026-08-27
Wu XiaobinPresident and COOSell280$380.00$106K
2026-08-12
OYLER JOHNChief Executive OfficerSell20.9K$358.41$7.5M
2026-08-12
OYLER JOHNChief Executive OfficerSell15.4K$357.63$5.5M
2026-08-12
OYLER JOHNChief Executive OfficerSell14.1K$359.12$5.1M
2026-08-12
OYLER JOHNChief Executive OfficerSell2.5K$356.43$896K
2026-08-12
OYLER JOHNChief Executive OfficerSell2.0K$354.71$702K
2026-08-11
filed 2026-08-12
OYLER JOHNChief Executive OfficerSell14.6K$361.47$5.3M
2026-08-11
filed 2026-08-12
OYLER JOHNChief Executive OfficerSell13.7K$359.32$4.9M
2026-08-11
filed 2026-08-12
OYLER JOHNChief Executive OfficerSell13.4K$363.45$4.9M
2026-08-11
filed 2026-08-12
OYLER JOHNChief Executive OfficerSell11.6K$362.34$4.2M
2026-08-11
filed 2026-08-12
OYLER JOHNChief Executive OfficerSell8.1K$360.33$2.9M
2026-08-11
filed 2026-08-12
OYLER JOHNChief Executive OfficerSell5.2K$364.31$1.9M

Reported non-derivative purchases and sales (codes P/S) — which may be open-market or private; excludes option exercises, grants, and shares withheld for taxes. Dates shown are the trade date; a Form 4 can be filed days to years later. A sale can be routine (e.g. a pre-set 10b5-1 plan), so read individual transactions in context. From SEC Form 4. Not investment advice.

Short interest

Total shares sold short as of each twice-monthly FINRA settlement. Rising short interest means more investors are positioned against the stock; days to cover estimates how many trading days of average volume that position represents.

Shares short
1.3M
settled 2026-08-14
Change vs prior
+44.9%
vs previous settlement
Days to cover
2.80
at avg daily volume
Avg daily volume
455.8K
FINRA reported
SettlementShares shortChangeDays to cover
2026-08-141.3M+44.9%2.80
2026-07-31880.6K-5.0%2.36
2026-07-15927.0K+17.1%2.63
2026-06-30791.6K-12.3%2.67
2026-06-15902.4K-17.2%2.90
2026-05-291.1M+4.1%4.89
2026-05-151.0M-5.8%4.15
2026-04-301.1M-3.7%5.85

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data, which is included at no additional charge for your own personal or professional use; republishing or redistributing it is not permitted. Settlement dates are shown; FINRA publishes each settlement about nine business days later, so the latest figure can be two to four weeks old. Not presented as a percentage of float. No FINRA endorsement of this product is implied. Not investment advice.

Income statement (as reported)

 FY2025FY2024FY2023FY2022FY2021
Revenue$5.34B$3.81B$2.46B$1.42B$1.18B
Gross profit$1.13B$1.01B
Operating income$447.1M$-568.2M$-1.21B$-1.79B$-1.44B
Net income$286.9M$-644.8M$-881.7M$-2.00B$-1.46B
Diluted EPS$0.19$-0.47$-0.65$-1.49$-1.21

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Balance sheet (as reported)

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Cash flow (as reported)

 FY2025FY2024FY2023FY2022FY2021
Operating cash flow$1.13B$-140.6M$-1.16B$-1.50B$-1.30B
Capital expenditure$185.8M$492.7M$561.9M$325.4M$262.9M
Free cash flow$941.7M$-633.3M$-1.72B$-1.82B$-1.56B

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.

Quarterly trend (as reported)

QuarterRevenueRevenue YoYNet incomeDiluted EPS
Q2 FY2026$1.71B29.6%$237.0M$0.16
Q1 FY2026$1.51B35.5%$227.4M$0.15
Q4 FY2025$1.50B32.8%$66.5M$0.04
Q3 FY2025$1.41B41.0%$124.8M$0.08
Q2 FY2025$1.32B41.6%$94.3M$0.06
Q1 FY2025$1.12B48.6%$1.3M$0.00
Q4 FY2024$1.13B77.8%$-151.9M$-0.11
Q3 FY2024$1.00B28.2%$-121.3M$-0.09

Latest 8 reported quarters, from company XBRL filings on SEC EDGAR.

Company facts

ExchangeNasdaq
SectorHealthcare
SIC industryPharmaceutical Preparations
Latest annual periodFY2025 (ended December 31, 2025)
Latest reported quarterQ2 FY2026 (ended June 30, 2026)
Oldest indexed filing2018
SEC CIK1651308

Selected SEC filings

10-K2026-02-26
View on EDGAR →
10-K/A2025-02-28
View on EDGAR →
10-Q2026-08-05
View on EDGAR →
10-Q2026-05-06
View on EDGAR →
10-Q2025-11-06
View on EDGAR →
10-Q2025-08-06
View on EDGAR →
8-K2026-08-26
View on EDGAR →
8-K2026-08-05
View on EDGAR →

Largest pharmaceutical peers

All pharmaceutical stocksAll Healthcare companies →

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Data sourced from SEC EDGAR. Figures are as-reported and may be unaudited or restated; verify against the source filing before relying on them. Informational only. Not investment advice.