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Nasdaq · Healthcare

Kiniksa Pharmaceuticals International, plc (KNSA)

As-reported financials and SEC filings for Kiniksa Pharmaceuticals International, plc. The latest annual period is FY2025. The latest reported quarter is Q1 FY2026. Financial statements come straight from the company’s EDGAR filings; valuation figures such as P/E and market cap use market data.

About Kiniksa Pharmaceuticals International, plc

Kiniksa Pharmaceuticals International, plc develops and commercializes pharmaceutical products. The company focuses on therapies for inflammatory and autoimmune diseases. It serves patients and healthcare providers globally.

Snapshot

Revenue
$677.6M
Revenue growth (YoY)
60.1%
Net income
$59.0M
Diluted EPS
$0.75
Gross margin
88.5%
Operating margin
11.4%
Net margin
8.7%
FCF margin
20.1%
ROE
10.4%
net income / fiscal-year-end equity
P/E
79.3×
trailing when available, otherwise FY EPS
Market cap
$6.13B
Long-term debt / equity
—
non-current term debt only

Fundamentals are from SEC filings for FY2025, the latest annual period (ended December 31, 2025). P/E and market cap are derived from stored market prices, last retrieved on a rolling basis and typically within the past week.

What changed at Kiniksa Pharmaceuticals International

  • Revenue grew 60.1% to $678M in FY2025, faster than the 56.6% the year before.
  • Operating margin turned positive at 11.4% in FY2025, from a 406.4% operating loss in FY2021.
  • Most recent quarter Q1 FY2026: revenue $214M, up 55.5% from Q1 FY2025.
  • Free cash flow was $136M in FY2025, 20.1% of revenue.
  • Net income turned positive at $59M in FY2025, from a $43M loss in FY2024.

Computed from the as-reported figures in the statements below. A change we cannot state from filed figures is left out rather than estimated.

Peer comparison

Where Kiniksa Pharmaceuticals International’s fundamentals sit among the 198 pharmaceutical companies. Each figure is ranked only against peers that report it, from lowest (left) to highest (right).

Gross margin88.5%
94th percentile of 69
Operating margin11.4%
67th percentile of 112
Net margin8.7%
68th percentile of 121
FCF margin20.1%
79th percentile of 110
Revenue growth (YoY)+60.1%
76th percentile of 188
ROE10.4%
75th percentile of 167
P/E79.3×
88th percentile of 50
Short interest6.41d
59th percentile of 197

Kiniksa Pharmaceuticals International’s gross margin of 88.5% ranks in the 94th percentile of the 69 pharmaceutical companies reporting it. Kiniksa Pharmaceuticals International’s P/E of 79.3 ranks in the 88th percentile of the 50 peers with a meaningful P/E.

No reported insider purchases (code P) in the last 90 days; 2 insider sales totaling $668,472. For context, about 15% of companies in the universe saw any reported insider purchase (code P) in the same window. Browse insider activity →

Percentiles describe where a figure sits among industry peers reporting it (100th = highest). They are position within a peer group, not a rating, and not investment advice. Short interest ranking uses days to cover from FINRA Consolidated Short Interest data; FINRA is the owner and source of that data, included at no additional charge.

Recent insider activity

Non-derivative buys and sells (codes P/S) reported by officers, directors and 10% owners on SEC Form 4.

Buys (90d)
0
code P
Bought (90d)
—
code P value
Sells (90d)
2
$668K
Reported activity
Net selling
by $ value, 90d
Trade dateInsiderTypeSharesPriceValue
2026-09-03
Michael R. MegnaCHIEF ACCOUNTING OFFICERSell4.6K$80.30$369K
2026-07-29
filed 2026-07-31
G. Bradley ColeDirectorSell3.7K$81.43$299K
2026-05-01
Sanj K. PatelCHAIRMAN & CEOSell48.6K$54.02$2.6M
2026-05-01
filed 2026-05-05
John F. PaoliniCHIEF MEDICAL OFFICERSell37.3K$53.52$2.0M
2026-05-01
filed 2026-05-05
John F. PaoliniCHIEF MEDICAL OFFICERSell21.1K$54.04$1.1M
2026-04-30
Sanj K. PatelCHAIRMAN & CEOSell2.1K$54.01$116K
2026-04-29
filed 2026-04-30
Sanj K. PatelCHAIRMAN & CEOSell22.5K$54.01$1.2M
2026-04-28
filed 2026-04-30
Sanj K. PatelCHAIRMAN & CEOSell243.6K$52.02$12.7M
2026-04-28
filed 2026-04-30
Sanj K. PatelCHAIRMAN & CEOSell113.7K$51.47$5.9M
2026-04-28
filed 2026-04-30
Sanj K. PatelCHAIRMAN & CEOSell74.6K$50.43$3.8M
2026-04-28
filed 2026-04-30
Sanj K. PatelCHAIRMAN & CEOSell51.8K$54.02$2.8M
2026-04-28
filed 2026-04-29
Barry D. QuartDirectorSell13.1K$50.10$656K

Reported non-derivative purchases and sales (codes P/S), which may be open-market or private. Excludes option exercises, grants, and shares withheld for taxes. Dates shown are the trade date; a Form 4 can be filed days to years later. A sale can be routine (e.g. a pre-set 10b5-1 plan), so read individual transactions in context. From SEC Form 4. Not investment advice.

Short interest

Total shares sold short as of each twice-monthly FINRA settlement. Rising short interest means more investors are positioned against the stock; days to cover estimates how many trading days of average volume that position represents.

Shares short
3.8M
settled 2026-09-30
Change vs prior
-2.5%
vs previous settlement
Days to cover
6.41
at avg daily volume
Avg daily volume
589.1K
FINRA reported
SettlementShares shortChangeDays to cover
2026-09-303.8M-2.5%6.41
2026-09-153.9M+2.3%7.21
2026-08-313.8M-11.6%8.69
2026-08-144.3M-0.8%9.56
2026-07-314.3M-4.3%4.99
2026-07-154.5M+8.6%6.85
2026-06-304.2M+41.0%2.88
2026-06-152.9M-3.1%5.73

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data, which is included at no additional charge for your own personal or professional use; republishing or redistributing it is not permitted. Settlement dates are shown; FINRA publishes each settlement about nine business days later, so the latest figure can be two to four weeks old. Not presented as a percentage of float. No FINRA endorsement of this product is implied. Not investment advice.

Income statement (as reported)

 FY2025FY2024FY2023FY2022FY2021
Revenue$677.6M$423.2M$270.3M$220.2M$38.5M
Gross profit
Operating income$77.2M$-45.6M$-25.2M$9.8M$-156.6M
Net income$59.0M$-43.2M$14.1M$183.4M$-157.9M
Diluted EPS$0.75$-0.60$0.20$2.60$-2.30

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (tap or hover a figure to see how it was calculated or what was filed). Full details: where the numbers come from.

Balance sheet (as reported)

 FY2025FY2024FY2023FY2022FY2021
Cash and equivalents$165.6M$183.6M$108.0M$122.7M$122.5M
Current assets$527.2M$331.8M$276.3M$243.1M$196.4M
Total assets$763.6M$580.6M$526.3M$459.7M$232.8M
Current liabilities$139.2M$100.6M$63.7M$47.1M$44.8M
Long-term debt—————
Total liabilities$196.0M$142.1M$87.5M$63.5M$47.8M
Total equity$567.6M$438.4M$438.8M$396.1M$185.0M

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (tap or hover a figure to see how it was calculated or what was filed). Full details: where the numbers come from.

Cash flow (as reported)

 FY2025FY2024FY2023FY2022FY2021
Operating cash flow$138.0M$25.7M$13.3M$5.8M$-126.3M
Capital expenditure$1.6M$277,000$130,000$105,000$415,000
Free cash flow

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (tap or hover a figure to see how it was calculated or what was filed). Full details: where the numbers come from.

Quarterly trend

QuarterRevenueRevenue YoYNet incomeDiluted EPS
Q1 FY2026$214.3M55.5%$22.6M$0.27
Q4 FY202565.0%
Q3 FY2025$180.9M61.2%$18.4M$0.23
Q2 FY2025$156.8M44.3%$17.8M$0.23
Q1 FY2025$137.8M72.5%$8.5M$0.11
Q4 FY202446.9%
Q3 FY2024$112.2M67.4%$-12.7M$-0.18
Q2 FY2024$108.6M52.0%$-3.9M$-0.06

Latest 8 quarters, from company XBRL filings on SEC EDGAR. A dotted underline marks a fourth-quarter figure we calculated from the full year and the first nine months. Revenue YoY is our calculation too: each quarter against the same quarter a year earlier.

Company facts

ExchangeNasdaq
SectorHealthcare
SIC industryPharmaceutical Preparations
Latest annual periodFY2025 (ended December 31, 2025)
Latest reported quarterQ1 FY2026 (ended March 31, 2026)
Oldest indexed filing2018
SEC CIK1730430

Selected SEC filings

10-Q2026-07-28
View on EDGAR →
10-Q2026-04-28
View on EDGAR →
8-K2026-07-28
View on EDGAR →
8-K2026-05-29
View on EDGAR →
8-K2026-05-26
View on EDGAR →
8-K2026-05-01
View on EDGAR →

Largest pharmaceutical peers

All pharmaceutical stocks →All Healthcare companies →

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Data sourced from SEC EDGAR. Figures are as-reported and may be unaudited or restated; verify against the source filing before relying on them. Informational only. Not investment advice.