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Nasdaq · Healthcare

Equillium, Inc. (EQ)

As-reported financials and SEC filings for Equillium, Inc. The latest annual period is FY2025. The latest reported quarter is Q2 FY2026. Financial statements come straight from the company’s EDGAR filings; valuation figures such as P/E and market cap use market data.

About Equillium, Inc.

Equillium, Inc. is a biotechnology company developing novel therapies for severe autoimmune and inflammatory disorders. Its main product candidates include EQ504, a selective aryl hydrocarbon receptor modulator aimed at treating ulcerative colitis and other gastrointestinal diseases, and EQ302, an oral inhibitor targeting IL-15 and IL-21 for gastrointestinal conditions such as celiac disease. The company focuses on advancing these therapies through preclinical and clinical development to address unmet medical needs in gastroenterology and related fields.

Snapshot

Revenue
—
Revenue growth (YoY)
—
Net income
$-22.4M
Diluted EPS
$-0.39
Gross margin
—
Operating margin
—
Net margin
—
FCF margin
—
ROE
-78.3%
net income / fiscal-year-end equity
P/E
n/m
not meaningful: a reported loss in the fiscal year or the trailing twelve months
Market cap
$83.7M
Long-term debt / equity
—
non-current term debt only

Fundamentals are from SEC filings for FY2025, the latest annual period (ended December 31, 2025). P/E and market cap are derived from stored market prices, last retrieved on a rolling basis and typically within the past week.

What changed at Equillium

  • Free cash flow was negative $23M in FY2025.
  • Net loss widened to $22M in FY2025, from $8M in FY2024.

Computed from the as-reported figures in the statements below. A change we cannot state from filed figures is left out rather than estimated.

Peer comparison

Where Equillium’s fundamentals sit among the 198 pharmaceutical companies. Each figure is ranked only against peers that report it, from lowest (left) to highest (right).

ROE-78.3%
20th percentile of 167
Short interest5.99d
55th percentile of 197

No reported insider transactions (codes P/S) in the last 90 days. For context, about 15% of companies in the universe saw any reported insider purchase (code P) in the same window. Browse insider activity →

Percentiles describe where a figure sits among industry peers reporting it (100th = highest). They are position within a peer group, not a rating, and not investment advice. Short interest ranking uses days to cover from FINRA Consolidated Short Interest data; FINRA is the owner and source of that data, included at no additional charge.

Institutional ownership

Held by 4 quant / multi-strat books among the superinvestors we track; no conviction manager currently reports a position.

Conviction investors
0
+4 quant / multi-strat
Initiated / added
1
1 new, 0 added
Reduced / exited
3
3 trimmed, 0 exited
Combined position
$3.2M
reported long value
InvestorAs ofPosition valueSharesChange
Renaissance TechnologiesquantQ2 2026$2.0M637.6KReduced
Two Sigma InvestmentsquantQ2 2026$661,930206.9KReduced
Citadel AdvisorsquantQ2 2026$318,91899.7KReduced
Millennium ManagementquantQ2 2026$137,08242.8KNew

From quarterly Form 13F filings, which can be up to 45 days delayed. Long US-listed positions only: excludes short positions, options, cash, bonds, and non-US holdings, so this is not a manager’s complete portfolio. Counts are of the investors we track, not all institutions. Not investment advice.

Recent insider activity

Non-derivative buys and sells (codes P/S) reported by officers, directors and 10% owners on SEC Form 4.

Buys (90d)
0
code P
Bought (90d)
—
code P value
Sells (90d)
0
—
Reported activity
Quiet
by $ value, 90d
Trade dateInsiderTypeSharesPriceValue
2026-06-05
Stephen ConnellyPresident and CSOSell31.0K$2.94$91K
2026-06-05
Christine ZedelmayerSr. Vice President and COOSell14.6K$2.93$43K
2026-06-04
filed 2026-06-05
Stephen ConnellyPresident and CSOSell200.0K$3.16$633K
2026-05-28
filed 2026-05-29
Penny TomPrincipal Accounting OfficerSell65.0K$2.95$192K
2026-05-28
filed 2026-05-29
Christine ZedelmayerSr. Vice President and COOSell55.6K$2.70$150K
2026-05-28
filed 2026-05-29
Christine ZedelmayerSr. Vice President and COOSell30.2K$2.98$90K
2026-05-28
filed 2026-05-29
Christine ZedelmayerSr. Vice President and COOSell200$2.71$542
2026-05-27
filed 2026-05-29
Christine ZedelmayerSr. Vice President and COOSell9.8K$2.70$27K

Reported non-derivative purchases and sales (codes P/S), which may be open-market or private. Excludes option exercises, grants, and shares withheld for taxes. Dates shown are the trade date; a Form 4 can be filed days to years later. A sale can be routine (e.g. a pre-set 10b5-1 plan), so read individual transactions in context. From SEC Form 4. Not investment advice.

Short interest

Total shares sold short as of each twice-monthly FINRA settlement. Rising short interest means more investors are positioned against the stock; days to cover estimates how many trading days of average volume that position represents.

Shares short
5.5M
settled 2026-09-30
Change vs prior
+0.7%
vs previous settlement
Days to cover
5.99
at avg daily volume
Avg daily volume
925.7K
FINRA reported
SettlementShares shortChangeDays to cover
2026-09-305.5M+0.7%5.99
2026-09-155.5M+2.4%15.03
2026-08-315.4M-3.0%13.10
2026-08-145.5M+2.2%10.00
2026-07-315.4M-2.7%11.84
2026-07-155.6M+8.9%4.54
2026-06-305.1M+8.6%6.66
2026-06-154.7M+30.6%3.10

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data, which is included at no additional charge for your own personal or professional use; republishing or redistributing it is not permitted. Settlement dates are shown; FINRA publishes each settlement about nine business days later, so the latest figure can be two to four weeks old. Not presented as a percentage of float. No FINRA endorsement of this product is implied. Not investment advice.

Income statement (as reported)

 FY2025FY2024FY2023FY2022FY2021
Revenue—$41.1M$36.1M$15.8M—
Gross profit—————
Operating income$-23.6M$-8.3M$-14.5M$-62.1M$-37.8M
Net income$-22.4M$-8.1M$-13.3M$-62.4M$-39.1M
Diluted EPS$-0.39$-0.23$-0.38$-1.85$-1.36

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (tap or hover a figure to see how it was calculated or what was filed). Full details: where the numbers come from.

Balance sheet (as reported)

 FY2025FY2024FY2023FY2022FY2021
Cash and equivalents$30.3M$18.1M$23.2M$59.1M$50.4M
Current assets$31.0M$25.0M$49.3M$76.7M$83.4M
Total assets$31.9M$25.6M$50.5M$78.4M$85.4M
Current liabilities$2.9M$6.4M$27.6M$32.0M$8.9M
Long-term debt———$3.2M$8.8M
Total liabilities$3.3M$6.5M$28.0M$46.5M$18.9M
Total equity$28.6M$19.1M$22.6M$31.9M$66.5M

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (tap or hover a figure to see how it was calculated or what was filed). Full details: where the numbers come from.

Cash flow (as reported)

 FY2025FY2024FY2023FY2022FY2021
Operating cash flow$-22.7M$-19.0M$-21.8M$-8.7M$-32.1M
Capital expenditure$48,000$85,000$50,000$279,000$57,000
Free cash flow

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (tap or hover a figure to see how it was calculated or what was filed). Full details: where the numbers come from.

Quarterly trend

QuarterRevenueRevenue YoYNet incomeDiluted EPS
Q2 FY2026——$-4.7M$-0.04
Q1 FY2026——$-5.3M$-0.06
Q4 FY2025——
Q3 FY2025——$-4.2M$-0.06
Q2 FY2025——$-5.7M—
Q1 FY2025——$-8.7M—
Q4 FY2024-52.3%—
Q3 FY2024$12.2M37.1%$-7,000$0.00

Latest 8 quarters, from company XBRL filings on SEC EDGAR. A dotted underline marks a fourth-quarter figure we calculated from the full year and the first nine months. Revenue YoY is our calculation too: each quarter against the same quarter a year earlier.

Company facts

ExchangeNasdaq
SectorHealthcare
SIC industryPharmaceutical Preparations
Latest annual periodFY2025 (ended December 31, 2025)
Latest reported quarterQ2 FY2026 (ended June 30, 2026)
Oldest indexed filing2018
SEC CIK1746466

Selected SEC filings

10-K2026-03-25
View on EDGAR →
10-Q2026-08-13
View on EDGAR →
10-Q2026-05-13
View on EDGAR →
8-K2026-10-05
View on EDGAR →
8-K2026-08-13
View on EDGAR →
8-K2026-05-29
View on EDGAR →
8-K2026-05-13
View on EDGAR →

Largest pharmaceutical peers

All pharmaceutical stocks →All Healthcare companies →

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Data sourced from SEC EDGAR. Figures are as-reported and may be unaudited or restated; verify against the source filing before relying on them. Informational only. Not investment advice.