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Nasdaq · Healthcare

Precision Biosciences Inc. (DTIL)

As-reported financials and SEC filings for Precision Biosciences Inc. The latest annual period is FY2025. The latest reported quarter is Q2 FY2026. Financial statements come straight from the company’s EDGAR filings; valuation figures such as P/E and market cap use market data.

About Precision Biosciences Inc.

Precision BioSciences, Inc. is a gene editing company based in Durham, North Carolina. It develops in vivo therapies for genetic and infectious diseases using its proprietary ARCUS genome editing platform. The company focuses on research and development activities and aims to obtain regulatory approval and commercialize its product candidates.

Snapshot

Revenue
$34.3M
Revenue growth (YoY)
-50.1%
Net income
$-45.7M
Diluted EPS
$-3.56
Gross margin
—
Operating margin
—
Net margin
—
FCF margin
—
ROE
-49.6%
net income / fiscal-year-end equity
P/E
n/m
not meaningful: a reported loss in the fiscal year or the trailing twelve months
Market cap
$170.3M
Long-term debt / equity
—
non-current term debt only

Fundamentals are from SEC filings for FY2025, the latest annual period (ended December 31, 2025). P/E and market cap are derived from stored market prices, last retrieved on a rolling basis and typically within the past week.

What changed at Precision Biosciences

  • Revenue fell 50.1% to $34M in FY2025, slower than the 41.0% the year before.
  • Operating margin is -152.2% in FY2025, -118.1 pp against -34.1% in FY2021.
  • Most recent quarter Q2 FY2026: revenue $0, down 100.0% from Q2 FY2025.
  • Free cash flow was negative $66M in FY2025.
  • Net income turned to a $46M loss in FY2025, from a $7M profit in FY2024.

Computed from the as-reported figures in the statements below. A change we cannot state from filed figures is left out rather than estimated.

Peer comparison

Where Precision Biosciences’s fundamentals sit among the 71 biotech companies. Each figure is ranked only against peers that report it, from lowest (left) to highest (right).

Revenue growth (YoY)-50.1%
10th percentile of 64
ROE-49.6%
35th percentile of 61
Short interest8.81d
70th percentile of 71

Precision Biosciences’s revenue growth of -50.1% ranks in the 10th percentile of the 64 biotech companies reporting it.

3 reported insider purchases (code P) totaling $29,501 in the last 90 days. For context, about 15% of companies in the universe saw any reported insider purchase (code P) in the same window. Browse insider activity →

Percentiles describe where a figure sits among industry peers reporting it (100th = highest). They are position within a peer group, not a rating, and not investment advice. Short interest ranking uses days to cover from FINRA Consolidated Short Interest data; FINRA is the owner and source of that data, included at no additional charge.

Institutional ownership

Held by 4 quant / multi-strat books among the superinvestors we track; no conviction manager currently reports a position.

Conviction investors
0
+4 quant / multi-strat
Initiated / added
0
0 new, 0 added
Reduced / exited
5
4 trimmed, 1 exited
Combined position
$3.1M
reported long value
InvestorAs ofPosition valueSharesChange
Two Sigma InvestmentsquantQ2 2026$1.9M237.9KReduced
Renaissance TechnologiesquantQ2 2026$539,01568.6KReduced
Citadel AdvisorsquantQ2 2026$538,81968.6KReduced
Point72 Asset ManagementquantQ2 2026$110,85714.1KReduced

No longer held by: Millennium Management (as of Q2 2026)

From quarterly Form 13F filings, which can be up to 45 days delayed. Long US-listed positions only: excludes short positions, options, cash, bonds, and non-US holdings, so this is not a manager’s complete portfolio. Counts are of the investors we track, not all institutions. Not investment advice.

Recent insider activity

Non-derivative buys and sells (codes P/S) reported by officers, directors and 10% owners on SEC Form 4. Multiple insiders have bought recently (a cluster buy).

Buys (90d)
3
3 insiders
Bought (90d)
$30K
code P value
Sells (90d)
0
—
Reported activity
Cluster buy
≥2 insiders buying
Trade dateInsiderTypeSharesPriceValue
2026-09-28
filed 2026-09-30
Stanley FrankelDirectorBuy1.0K$6.00$6K
2026-09-25
filed 2026-09-29
Geno J. GermanoDirectorBuy2.6K$6.28$16K
2026-09-25
filed 2026-09-29
Melinda BrownDirectorBuy1.1K$6.27$7K

Reported non-derivative purchases and sales (codes P/S), which may be open-market or private. Excludes option exercises, grants, and shares withheld for taxes. Dates shown are the trade date; a Form 4 can be filed days to years later. A sale can be routine (e.g. a pre-set 10b5-1 plan), so read individual transactions in context. From SEC Form 4. Not investment advice.

Short interest

Total shares sold short as of each twice-monthly FINRA settlement. Rising short interest means more investors are positioned against the stock; days to cover estimates how many trading days of average volume that position represents.

Shares short
2.5M
settled 2026-09-30
Change vs prior
+13.1%
vs previous settlement
Days to cover
8.81
at avg daily volume
Avg daily volume
285.3K
FINRA reported
SettlementShares shortChangeDays to cover
2026-09-302.5M+13.1%8.81
2026-09-152.2M-11.7%10.55
2026-08-312.5M+4.9%8.38
2026-08-142.4M-16.6%9.08
2026-07-312.9M+20.7%10.48
2026-07-152.4M+3.8%3.60
2026-06-302.3M+18.2%3.48
2026-06-151.9M+16.1%5.42

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data, which is included at no additional charge for your own personal or professional use; republishing or redistributing it is not permitted. Settlement dates are shown; FINRA publishes each settlement about nine business days later, so the latest figure can be two to four weeks old. Not presented as a percentage of float. No FINRA endorsement of this product is implied. Not investment advice.

Income statement (as reported)

 FY2025FY2024FY2023FY2022FY2021
Revenue$34.3M$68.7M$48.7M$25.1M$115.5M
Gross profit—————
Operating income$-52.1M$-26.2M$-43.7M$-62.3M$-39.4M
Net income$-45.7M$7.2M$-61.3M$-111.6M$-30.6M
Diluted EPS$-3.56$1.04$-15.96$-38.10

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (tap or hover a figure to see how it was calculated or what was filed). Full details: where the numbers come from.

Balance sheet (as reported)

 FY2025FY2024FY2023FY2022FY2021
Cash and equivalents$110.8M$85.9M$116.7M$189.6M$143.7M
Current assets$118.7M$95.0M$136.4M$199.1M$161.8M
Total assets$154.4M$136.4M$159.8M$238.2M$211.5M
Current liabilities$8.9M$15.0M$50.0M$59.7M$36.0M
Long-term debt———$22.2M$2.5M
Total liabilities$62.2M$80.0M$140.9M$177.7M$120.3M
Total equity$92.2M$56.4M$18.9M$60.4M$91.2M

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (tap or hover a figure to see how it was calculated or what was filed). Full details: where the numbers come from.

Cash flow (as reported)

 FY2025FY2024FY2023FY2022FY2021
Operating cash flow$-65.8M$-58.4M$-84.1M$-45.8M$-10.9M
Capital expenditure$85,000$250,000$2.0M$3.3M$5.1M
Free cash flow

Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (tap or hover a figure to see how it was calculated or what was filed). Full details: where the numbers come from.

Quarterly trend

QuarterRevenueRevenue YoYNet incomeDiluted EPS
Q2 FY2026$0-100.0%$-32.7M$-1.26
Q1 FY2026$10.8M37272.4%$-18.4M$-0.75
Q4 FY2025——
Q3 FY2025$13,000-97.7%$-21.8M—
Q2 FY2025$18,000-100.0%$-23.5M—
Q1 FY2025$29,000-99.8%$-20.6M—
Q4 FY2024-90.9%—
Q3 FY2024$576,000-95.6%$-16.4M—

Latest 8 quarters, from company XBRL filings on SEC EDGAR. A dotted underline marks a fourth-quarter figure we calculated from the full year and the first nine months. Revenue YoY is our calculation too: each quarter against the same quarter a year earlier.

Company facts

ExchangeNasdaq
SectorHealthcare
SIC industryBiological Products, (No Diagnostic Substances)
Latest annual periodFY2025 (ended December 31, 2025)
Latest reported quarterQ2 FY2026 (ended June 30, 2026)
Oldest indexed filing2006
SEC CIK1357874

Selected SEC filings

10-K2026-03-12
View on EDGAR →
10-Q2026-08-06
View on EDGAR →
10-Q2026-05-05
View on EDGAR →
8-K2026-08-24
View on EDGAR →
8-K2026-08-06
View on EDGAR →
8-K2026-07-27
View on EDGAR →
8-K2026-07-01
View on EDGAR →

Largest biotech peers

All biotech stocks →All Healthcare companies →

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Data sourced from SEC EDGAR. Figures are as-reported and may be unaudited or restated; verify against the source filing before relying on them. Informational only. Not investment advice.