CRISPR Therapeutics AG (CRSP)
As-reported financials and SEC filings for CRISPR Therapeutics AG. The latest annual period is FY2025. The latest reported quarter is Q2 FY2026. Financial statements come straight from the company’s EDGAR filings; valuation figures such as P/E and market cap use market data.
About CRISPR Therapeutics AG
CRISPR Therapeutics AG is a biopharmaceutical company that develops gene-based medicines using CRISPR/Cas9 gene-editing technology. Its main products include CASGEVY, an approved gene-edited cell therapy for sickle cell disease and beta thalassemia, and investigational therapies for autoimmune diseases, oncology, and diabetes. The company serves patients with serious genetic and rare diseases through both ex vivo and in vivo gene editing approaches.
Snapshot
Fundamentals are from SEC filings for FY2025, the latest annual period (ended December 31, 2025). P/E and market cap are derived from stored market prices, last retrieved on a rolling basis and typically within the past week.
What changed at CRISPR Therapeutics
- Revenue fell 90.6% to $4M in FY2025, after a 89.9% decline the year before.
- Operating margin is now a 18933.6% loss in FY2025, from 40.8% in FY2021.
- Most recent quarter Q2 FY2026: revenue $10M, up 1041.4% from Q2 FY2025.
- Free cash flow was negative $346M in FY2025.
- Net loss widened to $582M in FY2025, from $366M in FY2024.
Computed from the as-reported figures in the statements below. A change we cannot state from filed figures is left out rather than estimated.
Peer comparison
Where CRISPR Therapeutics’s fundamentals sit among the 71 biotech companies. Each figure is ranked only against peers that report it, from lowest (left) to highest (right).
CRISPR Therapeutics’s long-term debt to equity of 0.00 ranks in the 1st percentile of the 20 biotech companies reporting it. CRISPR Therapeutics’s revenue growth of -90.6% ranks in the 2nd percentile of the 64 biotech companies reporting it.
No reported insider transactions (codes P/S) in the last 90 days. For context, about 15% of companies in the universe saw any reported insider purchase (code P) in the same window. Browse insider activity →
Percentiles describe where a figure sits among industry peers reporting it (100th = highest). They are position within a peer group, not a rating, and not investment advice. Short interest ranking uses days to cover from FINRA Consolidated Short Interest data; FINRA is the owner and source of that data, included at no additional charge.
Recent insider activity
Non-derivative buys and sells (codes P/S) reported by officers, directors and 10% owners on SEC Form 4.
| Trade date | Insider | Type | Shares | Price | Value |
|---|---|---|---|---|---|
2026-05-29 filed 2026-06-01 | Patel NaimishChief Medical Officer | Sell | 3.8K | $55.62 | $211K |
Reported non-derivative purchases and sales (codes P/S) — which may be open-market or private; excludes option exercises, grants, and shares withheld for taxes. Dates shown are the trade date; a Form 4 can be filed days to years later. A sale can be routine (e.g. a pre-set 10b5-1 plan), so read individual transactions in context. From SEC Form 4. Not investment advice.
Short interest
Total shares sold short as of each twice-monthly FINRA settlement. Rising short interest means more investors are positioned against the stock; days to cover estimates how many trading days of average volume that position represents.
| Settlement | Shares short | Change | Days to cover |
|---|---|---|---|
| 2026-08-14 | 18.7M | -0.4% | 15.58 |
| 2026-07-31 | 18.8M | -5.0% | 11.52 |
| 2026-07-15 | 19.8M | -2.9% | 11.56 |
| 2026-06-30 | 20.4M | -23.2% | 11.65 |
| 2026-06-15 | 26.6M | +22.6% | 16.35 |
| 2026-05-29 | 21.7M | -20.6% | 12.29 |
| 2026-05-15 | 27.3M | +21.4% | 16.54 |
| 2026-04-30 | 22.5M | -1.2% | 11.91 |
Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data, which is included at no additional charge for your own personal or professional use; republishing or redistributing it is not permitted. Settlement dates are shown; FINRA publishes each settlement about nine business days later, so the latest figure can be two to four weeks old. Not presented as a percentage of float. No FINRA endorsement of this product is implied. Not investment advice.
Income statement (as reported)
| FY2025 | FY2024 | FY2023 | FY2022 | FY2021 | |
|---|---|---|---|---|---|
| Revenue | $3.5M | $37.3M | $371.2M | $1.2M | $915.0M |
| Gross profit | — | — | — | — | — |
| Operating income | $-664.6M | $-466.6M | $-222.5M | $-673.2M | $373.5M |
| Net income | $-581.6M | $-366.3M | $-153.6M | $-650.2M | $377.7M |
| Diluted EPS | $-6.47 | $-4.34 | $-1.94 | $-8.36 | $4.70 |
Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.
Balance sheet (as reported)
| FY2025 | FY2024 | FY2023 | FY2022 | FY2021 | |
|---|---|---|---|---|---|
| Cash and equivalents | $347.6M | $298.3M | $389.5M | $211.9M | $923.0M |
| Current assets | $1.99B | $1.94B | $1.91B | $1.85B | $2.42B |
| Total assets | $2.27B | $2.24B | $2.23B | $2.24B | $2.75B |
| Current liabilities | $149.1M | $87.8M | $108.8M | $121.1M | $119.9M |
| Long-term debt | $0 | — | — | — | — |
| Total liabilities | $343.4M | $310.0M | $346.8M | $367.6M | $352.4M |
| Total equity | $1.92B | $1.93B | $1.88B | $1.88B | $2.40B |
Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.
Cash flow (as reported)
| FY2025 | FY2024 | FY2023 | FY2022 | FY2021 | |
|---|---|---|---|---|---|
| Operating cash flow | $-345.0M | $-142.8M | $-260.4M | $-495.7M | $539.0M |
| Capital expenditure | $914,000 | $1.9M | $9.5M | $37.2M | $81.7M |
| Free cash flow | $-345.9M | $-144.7M | $-269.8M | $-532.9M | $457.3M |
Figures as reported to the SEC. Underlined values link to the filing they came from; dotted values are calculated by us from reported figures; “adj” means restated for a stock split (hover to see the figure as filed). Full details: where the numbers come from.
Quarterly trend (as reported)
| Quarter | Revenue | Revenue YoY | Net income | Diluted EPS |
|---|---|---|---|---|
| Q2 FY2026 | $10.2M | 1041.4% | $-91.2M | $-0.94 |
| Q1 FY2026 | $1.5M | 68.6% | $-122.9M | $-1.28 |
| Q4 FY2025 | $864,000 | — | $-130.6M | $-1.37 |
| Q3 FY2025 | $889,000 | 47.7% | $-106.4M | $-1.17 |
| Q2 FY2025 | $892,000 | 72.5% | $-208.5M | $-2.40 |
| Q1 FY2025 | $865,000 | 71.6% | $-136.0M | $-1.58 |
| Q4 FY2024 | — | — | $-37.3M | $-0.44 |
| Q3 FY2024 | $602,000 | — | $-85.9M | $-1.01 |
Latest 8 reported quarters, from company XBRL filings on SEC EDGAR.
Company facts
Selected SEC filings
Largest biotech peers
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Data sourced from SEC EDGAR. Figures are as-reported and may be unaudited or restated; verify against the source filing before relying on them. Informational only. Not investment advice.