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Medline vs Stryker (MDLN vs SYK)

Side by side from their SEC filings: revenue, margins, growth, returns and valuation, plus short interest, insider activity and institutional ownership.

Medline is the larger company by revenue ($28.4B vs $25.1B). Stryker carries the larger market value ($127.1B vs $72.3B). Stryker runs the higher operating margin (19.5% vs 7.8%). Medline trades at the lower trailing P/E (35.3x vs 38.4x).

About Medline

Medline Inc. is a provider of medical-surgical products and supply chain solutions serving various healthcare settings such as hospitals, surgery centers, and physician offices. The company offers approximately 335,000 products, including surgical kits, gloves, wound care items, and diagnostic equipment, through its Medline Brand and Supply Chain Solutions segments. Medline operates a network of global distribution centers and its own fleet of trucks to deliver products and supply chain services to healthcare providers.

About Stryker

Stryker Corporation develops and sells medical technologies globally, focusing on MedSurg, Neurotechnology, and Orthopaedics. Its products include surgical equipment, patient care technologies, implants for joint replacement and trauma surgeries, and robotic-assisted surgical systems. The company serves healthcare providers such as doctors, hospitals, and other medical facilities in approximately 61 countries.

Head to head (MDLN FY2025 vs SYK FY2025)

MetricMDLNFY2025SYKFY2025
Revenue$28.43B$25.12B
Revenue growth (YoY)11.2%
Gross margin26.4%64.0%
Operating margin7.8%19.5%
Net margin4.1%12.9%
Net income$1.16B$3.25B
Diluted EPS$-0.01$8.40
FCF margin4.6%17.1%
ROE6.0%14.5%
Debt / equity0.6×0.7×
Market cap$72.30B$127.06B
P/E (TTM)35.3×38.4×

Fundamentals are from each company’s SEC filings (MDLN FY2025, SYK FY2025). P/E and market cap are derived from recent market prices and update daily.

Five-year trend (as reported)

MDLN by fiscal yearFY2022FY2023FY2024FY2025
Revenue$23.23B$25.51B$28.43B
Net income$234.0M$1.16B$1.15B$1.16B
Operating margin5.4%8.4%7.8%
SYK by fiscal yearFY2021FY2022FY2023FY2024FY2025
Revenue$17.11B$18.45B$20.50B$22.59B$25.12B
Net income$1.99B$2.36B$3.17B$2.99B$3.25B
Operating margin15.1%15.4%19.0%16.3%19.5%

Medline and Stryker use different fiscal calendars (MDLN's FY2025 ended 2025-12-31, SYK's FY2025 ended 2025-12-31), so their fiscal years are shown separately rather than forced into one timeline.

Peer standing

Where each company ranks among the 88 medical device companies, on the same scale. Each figure is ranked only against peers that report it. Percentiles describe position in the distribution, not a rating.

MetricMDLNSYK
Gross margin
26.4%3rd percentile of 77
64.0%55th percentile of 77
Operating margin
7.8%66th percentile of 80
19.5%91st percentile of 80
Net margin
4.1%66th percentile of 81
12.9%83rd percentile of 81
FCF margin
4.6%63rd percentile of 74
17.1%86th percentile of 74
ROE
6.0%65th percentile of 79
14.5%82nd percentile of 79
P/E (TTM)
35.3×61st percentile of 32
38.4×71st percentile of 32
Debt / equity
0.65×60th percentile of 54
0.66×62nd percentile of 54
Short interest (days to cover)
3.73d53rd percentile of 88
2.36d31st percentile of 88

Short interest

FINRA settlement dataMDLNSYK
Shares sold short36.3M6.9M
Change vs prior settlement+31.3%+12.7%
Days to cover3.732.36
As of settlement2026-06-302026-06-30

Source: FINRA Consolidated Short Interest. FINRA is the owner and source of the FINRA-supplied data; republishing or redistributing it is not permitted. Not presented as a percentage of float. No FINRA endorsement of this product is implied.

Insider activity (last 90 days)

Form 4 open-market activityMDLNSYK
Buys1 ($170,750)0
Sells14 ($3.60B)14 ($100.7M)

Open-market purchases and sales reported on SEC Form 4 (grants, exercises and tax withholding excluded). For context, about 16% of covered companies saw any open-market insider buy in a 90-day window.

Held by the same investors

6 tracked 13F managers hold both Medline and Stryker as of their latest quarterly filings: Citadel Advisors, Gotham Asset Management, Millennium Management, Point72 Asset Management, Renaissance Technologies, Two Sigma Investments. See which superinvestors hold your own portfolio with the smart money checker.

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Data sourced from SEC EDGAR (public domain). Figures are as-reported and may be unaudited or restated; verify against the source filings before relying on them. Comparisons are descriptive (higher or lower on a reported figure), not a rating or a recommendation. Informational only. Not investment advice.